Background Butyrate, a short‐chain fatty acid, is a main end‐product of intestinal microbial
fermentation of mainly dietary fibre. Butyrate is an important energy source for intestinal …

The gastrointestinal tract consists of an enormous surface area that is optimized to efficiently
absorb nutrients, water, and electrolytes from food. At the same time, it needs to provide a …

The gut barrier plays a crucial role by spatially compartmentalizing bacteria to the lumen
through the production of secreted mucus and is fortified by the production of secretory IgA …

Intestinal barrier integrity is a prerequisite for homeostasis of mucosal function, which is
balanced to maximise absorptive capacity, while maintaining efficient defensive reactions …

Malnutrition is observed frequently and is an important complication in patients with Crohn
disease (CD). The pathophysiology of malnutrition in this disorder is complex. To obtain a …

Health claims for probiotics are evaluated by the Panel on Dietetic Products, Nutrition and
Allergies of the European Food Safety Authority. Despite a substantial amount of basic and …

Background & Aims: Appendectomy has been pointed sis of IBD has been discussed. Four
fully published stud-out as a protective factor for ulcerative colitis (UC). ies have shown a …

Background Faecal microbiota transplantation (FMT) is an emerging treatment modality, but
its current clinical use and organisation are unknown. We aimed to describe the clinical use …

Background A subset of irritable bowel syndrome (IBS) patients, denoted post‐infectious IBS
(PI‐IBS), develop symptoms after an enteric infection. Bacterial dysbiosis and mucosal …

Background Faecal microbiota transplantation or transfer (FMT) aims at replacing or
reinforcing the gut microbiota of a patient with the microbiota from a healthy donor. Not many …