The potent sphingolipid metabolite sphingosine 1-phosphate is produced by
phosphorylation of sphingosine catalyzed by sphingosine kinase (SphK) types 1 and 2. In …

There are two isoforms of sphingosine kinase (SphK) that catalyze the formation of
sphingosine 1-phosphate, a potent sphingolipid mediator. Whereas SphK1 stimulates …

Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The
bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to …

Selecting a suitable equation to represent a set of multifactor data that was collected for
other purposes in a plant, pilot-plant, or laboratory can be troublesome. If there are k …

This article develops and tests a “fair price” theory which is essentially contradictory to
Weber's Law. As price levels rise, a constant price differential between brands becomes …

New soluble chromogenic substrates were prepared for specific and rapid assays of endo-1,
4-β-xylanases and endo-1, 4-β-glucanases. A soluble beechwood 4-O-methyl-d-glucurono …

The lysophospholipid mediators, lysophosphatidic acid (LPA) and sphingosine-1-phosphate
(S1P), are responsible for cell signaling in diverse pathways including survival, proliferation …

The process of neurite extension after activation of the TrkA tyrosine kinase receptor by
nerve growth factor (NGF) involves complex signaling pathways. Stimulation of sphingosine …

Background Humans are ubiquitously exposed to multiple environmental contaminants.
Consequences of combined action on the reproductive system remain unknown. This study …

The role of Toll-like receptors (TLRs) in the recognition of extracellular and facultative
intracellular bacteria by the innate immune system has been extensively studied, but their …