[HTML][HTML] Pathophysiology and treatment of focal segmental glomerulosclerosis: the role of animal models

SML de Mik, MJ Hoogduijn, RW de Bruin, FJMF Dor - BMC nephrology, 2013 - Springer
Focal segmental glomerulosclerosis (FSGS) is a kidney disease with progressive glomerular
scarring and a clinical presentation of nephrotic syndrome. FSGS is a common primary …

Heritable hydronephrosis in a mutant strain of brown Norway rats.

BJ Cohen, RW De Bruin, WJ Kort - Laboratory Animal Care, 1970 - cabdirect.org
A colony of inbred Brown Norway (BN) rats was screened for hydronephrosis by intravenous
pyelo-graphy. 44 of 142 two-mth-old rats (31%) had unilateral or bilateral hydronephrosis of …

Successful treatment of colon cancer in rats with recombinant interferon-gamma.

JN Ijzermans, RL Marquet, E Bouwman… - British journal of …, 1987 - ncbi.nlm.nih.gov
The lymphokine interferon gamma (IFN-y), is produced by mitogen or antigen-stimulated T-
lymphocytes (Nathan et al., 1981). Compared to IFNa and several differences in biological …

Value of in vivo electrophysiological measurements to evaluate canine small bowel autotransplants.

MA Meijssen, E Heineman, RW De Bruin, HJ Veeze… - Gut, 1991 - gut.bmj.com
This study aimed to develop a non-invasive method for in vivo measurement of the
transepithelial potential difference in the canine small bowel and to evaluate this parameter …

[PDF][PDF] The effect of cyclosporine A in small bowel transplantation in rats is dependent on the rat strain combination used

RW De Bruin, RE Saat, E Heineman, J Jeekel… - Transplant …, 1990 - repub.eur.nl
Cyclosporine A (CsA) is very effective in preventing the rejection of small bowel allografts in
some reported rat models. We have tested the effect of different CsA dosages on the survival …

Site-specific antitumour effects of 2 pyrimidinone compounds in rats.

AM Eggermont, RL Marquet, RW De Bruin… - British journal of …, 1986 - ncbi.nlm.nih.gov
Recently a series of 5-halo-6-phenyl pyrimidinones has been found to induce interferon
production in several animal species (Stringfellow et al., 1980) and in man (Earhart et al …

Total orthotopic allogeneic small bowel transplantation in rats: effect of allograft irradiation combined with cyclosporine-A therapy.

RE Saat, RW de Bruin, E Heineman, J Jeekel… - Gut, 1991 - gut.bmj.com
Rejection and graft versus host disease are prominent features in small bowel
allotransplantation in rats. Cyclosporine treatment of the recipient and irradiation of the …

Treatment with rIFN-gamma has no effect on cardiac allograft rejection.

JN Ijzermans, E Bouwman, RW De Bruin, J Jeekel… - …, 1991 - ncbi.nlm.nih.gov
The effect of recombinant rat interferon-gamma (rRIFN-gamma) on allograft rejection was
studied in two rat heart transplantation models. Recipients were treated with rRIFN-gamma …

A Preoperative Protein Free Diet Protects Against Renal Ischemia and Reperfusion Injury: 1658

T Saat, T van Ginhoven, M Verweij… - …, 2012 - journals.lww.com
Background: Ischemia and reperfusion (I/R) injury is a serious and common complication of
organ transplantation. Previously we showed that both two weeks of 30% dietary restriction …

[CITATION][C] Clinical effects of long-term lymphokine injections in patients with advanced carcinoma

DC Dumonde, MS Pulley, D O'Connell… - International Journal of …, 1980 - Pergamon