[HTML][HTML] AMPK re-activation suppresses hepatic steatosis but its downregulation does not promote fatty liver development
N Boudaba, A Marion, C Huet, R Pierre, B Viollet… - …, 2018 - thelancet.com
Nonalcoholic fatty liver disease is a highly prevalent component of disorders associated with
disrupted energy homeostasis. Although dysregulation of the energy sensor AMP-activated …
disrupted energy homeostasis. Although dysregulation of the energy sensor AMP-activated …
[HTML][HTML] A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes
M Dos Santos, S Backer, F Auradé, MMK Wong… - Nature …, 2022 - nature.com
The contractile properties of adult myofibers are shaped by their Myosin heavy chain isoform
content. Here, we identify by snATAC-seq a 42 kb super-enhancer at the locus regrouping …
content. Here, we identify by snATAC-seq a 42 kb super-enhancer at the locus regrouping …
Driving Role of Interleukin‐2–Related Regulatory CD4+ T Cell Deficiency in the Development of Lung Fibrosis and Vascular Remodeling in a Mouse Model of …
C Frantz, A Cauvet, A Durand, V Gonzalez… - Arthritis & …, 2022 - Wiley Online Library
Objective Systemic sclerosis (SSc) is a debilitating autoimmune disease characterized by
severe lung outcomes resulting in reduced life expectancy. Fra‐2–transgenic mice offer the …
severe lung outcomes resulting in reduced life expectancy. Fra‐2–transgenic mice offer the …
Managerial style and well‐being among psychiatric nurses: A prospective study
N Gillet, A Le Gouge, R Pierre, J Bongro… - Journal of psychiatric …, 2019 - Wiley Online Library
Accessible summary What is known on the subject? Numerous studies have shown that
organizational and managerial factors have significant effects on nurses' workplace well …
organizational and managerial factors have significant effects on nurses' workplace well …
[HTML][HTML] Deletion of the Spata3 Gene Induces Sperm Alterations and In Vitro Hypofertility in Mice
MS Girault, S Dupuis, C Ialy-Radio, L Stouvenel… - International Journal of …, 2021 - mdpi.com
Thanks to the analysis of an Interspecific Recombinant Congenic Strain (IRCS), we
previously defined the Mafq1 quantitative trait locus as an interval on mouse Chromosome 1 …
previously defined the Mafq1 quantitative trait locus as an interval on mouse Chromosome 1 …
Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling
J Javary, N Allain-Courtois, N Saucisse, P Costet… - Gut, 2018 - gut.bmj.com
Objective The AAA+ ATPase Reptin is overexpressed in hepatocellular carcinoma and
preclinical studies indicate that it could be a relevant therapeutic target. However, its …
preclinical studies indicate that it could be a relevant therapeutic target. However, its …
Gain-of-function prolactin receptor variants are not associated with breast cancer and multiple fibroadenoma risk
Z Chakhtoura, F Laki, M Bernadet… - The Journal of …, 2016 - academic.oup.com
Context: In a cohort of 95 women with multiple breast fibroadenomas (MFAs), we recently
identified patients harboring germline heterozygous variants of the prolactin receptor …
identified patients harboring germline heterozygous variants of the prolactin receptor …
[HTML][HTML] Generation and Characterization of a Transgenic Mouse That Specifically Expresses the Cre Recombinase in Spermatids
C Gobé, C Ialy-Radio, R Pierre, J Cocquet - Genes, 2023 - mdpi.com
Spermiogenesis is the step during which post-meiotic cells, called spermatids, undergo
numerous morphological changes and differentiate into spermatozoa. Thousands of genes …
numerous morphological changes and differentiate into spermatozoa. Thousands of genes …
[HTML][HTML] Cyclic fertilin-derived peptide stimulates in vitro human embryo development
AL Denizot, A L'Hostis, A Sallem, S Favier, R Pierre… - F&S Science, 2022 - Elsevier
Objective To study the cyclic fertilin peptide effects on preimplantation human
embryogenesis. Cyclic fertilin peptide reproduces the structure of the binding site of the …
embryogenesis. Cyclic fertilin peptide reproduces the structure of the binding site of the …
A fast Myh super enhancer dictates adult muscle fiber phenotype through competitive interactions with the fast Myh genes
The contractile properties of adult myofibers are shaped by their Myosin heavy chain (MYH)
isoform content. We identify by snATAC-seq a 42kb super-enhancer (SE) at the locus …
isoform content. We identify by snATAC-seq a 42kb super-enhancer (SE) at the locus …