[HTML][HTML] Validation of transient elastography and comparison with spleen length measurement for staging of fibrosis and clinical prognosis in primary sclerosing …

H Ehlken, R Wroblewski, C Corpechot, L Arrive… - PloS one, 2016 - journals.plos.org
Background Patients with primary sclerosing cholangitis (PSC) develop progressive liver
fibrosis and end-stage liver disease. Non-invasive and widely available parameters are …

Down-regulation of CD73 on B cells of patients with viremic HIV correlates with B cell activation and disease progression

ES Kim, C Ackermann, I Tóth, P Dierks… - Journal of Leucocyte …, 2017 - academic.oup.com
Recently, alterations of the T cell expression of the ectonucleotidases, CD39 and CD73,
during HIV infection have been described. Here, peripheral (n= 70) and lymph nodal B cells …

Spleen size for the prediction of clinical outcome in patients with primary sclerosing cholangitis

H Ehlken, R Wroblewski, C Corpechot, L Arrivé… - Gut, 2016 - gut.bmj.com
Dear Sir, We read with interest the work of van der Meer et al1 who propose a risk score for
patients with chronic Hepatitis C. The authors demonstrate that the assessment of readily …

[PDF][PDF] Opposing role of tumor necrosis factor receptor 1 signaling in T cell–mediated hepatitis and bacterial infection in mice

R Wroblewski, M Armaka, V Kondylis… - …, 2016 - Wiley Online Library
Death receptor (DR) ligands such as tumor necrosis factor (TNF) have been identified as
fundamental mediators of liver damage both in mouse models and in humans. While the …

Brief report: increased frequency of CD39+ CD56bright natural killer cells in HIV-1 infection correlates with immune activation and disease progression

P Dierks, R Wroblewski, JM Eberhard… - JAIDS Journal of …, 2017 - journals.lww.com
The expression pattern of the ectonucleotidases CD39 and CD73 on natural killer (NK) cells
was examined in peripheral blood mononuclear cell of 61 HIV-1–infected patients …

[HTML][HTML] Frequent detection of functional hyposplenism via assessment of pitted erythrocytes in patients with advanced liver cirrhosis

MH Wehmeyer, H Sekhri, R Wroblewski, A Galante… - Plos one, 2022 - journals.plos.org
Background Asplenia or functional hyposplenism are risk factors for severe infections, and
vaccinations against encapsulated bacteria are advised. There are only limited data …

[HTML][HTML] Rolle der Todesrezeptoren in immunvermittelten Lebererkrankungen

RM Wroblewski - 2015 - ediss.sub.uni-hamburg.de
Die Hauptaufgabe des Immunsystems ist der Schutz des Organismus vor Infektionen.
Angeborene und adaptive Immunantwort kooperieren hierbei in der Beseitigung von …

[CITATION][C] Increased frequency of CD39+ CD56 bright Natural Killer cells in HIV-1 infection correlates with immune activation and disease progression.

P Dierks, R Wroblewski, JM Eberhard, G Martrus… - JAIDS Journal of …, 2016 - LWW