User profiles for "author:Raquel Mejias-Luque"

Raquel Mejías-Luque

Technical University of Munich
Verified email at tum.de
Cited by 2490

[HTML][HTML] H. pylori Virulence Factors: Influence on Immune System and Pathology

B Kalali, R Mejías-Luque, A Javaheri… - Mediators of …, 2014 - hindawi.com
Helicobacter pylori is the most widespread chronic bacterial agent in humans and is well
recognized for its association with ulcer disease and gastric cancer, with both representing …

Immune Evasion Strategies and Persistence of Helicobacter pylori

R Mejías-Luque, M Gerhard - Molecular Pathogenesis and Signal …, 2017 - Springer
Helicobacter pylori infection is commonly acquired during childhood, can persist lifelong if
not treated, and can cause different gastric pathologies, including chronic gastritis, peptic …

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs

A Javaheri, T Kruse, K Moonens, R Mejías-Luque… - Nature …, 2016 - nature.com
Helicobacter pylori specifically colonizes the human gastric epithelium and is the major
causative agent for ulcer disease and gastric cancer development. Here, we identify …

Effect of Helicobacter pylori on gastrointestinal microbiota: a population-based study in Linqu, a high-risk area of gastric cancer

Y Guo, Y Zhang, M Gerhard, JJ Gao, R Mejias-Luque… - Gut, 2020 - gut.bmj.com
Objective Gastrointestinal microbiota may be involved in Helicobacter pylori-associated
gastric cancer development. The aim of this study was to explore the possible microbial …

[HTML][HTML] SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer

J Neumann, F Bahr, D Horst, L Kriegl, J Engel… - BMC cancer, 2011 - Springer
Background The transcription factor SOX2, which is involved in the induction of pluripotent
stem cells and contributes to colorectal carcinogenesis, is associated with a poor prognosis …

[HTML][HTML] Association Between Gut Microbiota and Helicobacter pylori-Related Gastric Lesions in a High-Risk Population of Gastric Cancer

JJ Gao, Y Zhang, M Gerhard… - Frontiers in cellular …, 2018 - frontiersin.org
Eradication of Helicobacter pylori has been found to be effective for gastric cancer
prevention, but uncertainties remain about the possible adverse consequences such as the …

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

K Hütz, R Mejías-Luque, K Farsakova, M Ogris… - …, 2014 - academic.oup.com
Gastric cancer (GC) is still one of the most common causes of cancer-related death
worldwide, which is mainly attributable to late diagnosis and poor treatment options …

[HTML][HTML] Effects of Helicobacter pylori adhesin HopQ binding to CEACAM receptors in the human stomach

QA Nguyen, L Schmitt, R Mejías-Luque… - Frontiers in …, 2023 - frontiersin.org
Helicobacter pylori has developed several strategies using its diverse virulence factors to
trigger and, at the same time, limit the host's inflammatory responses in order to establish a …

Helicobacter pylori cytotoxin-associated gene A impairs human dendritic cell maturation and function through IL-10–mediated activation of STAT3

R Kaebisch, R Mejías-Luque, C Prinz… - The Journal of …, 2014 - journals.aai.org
Helicobacter pylori infection induces chronic gastric inflammation that can progress to
cancer. In this process, the virulence factor cytotoxin-associated gene A (CagA) plays a …

Helicobacter pylori adhesin HopQ disrupts trans dimerization in human CEACAMs

K Moonens, Y Hamway, M Neddermann… - The EMBO …, 2018 - embopress.org
The human gastric pathogen Helicobacter pylori is a major causative agent of gastritis,
peptic ulcer disease, and gastric cancer. As part of its adhesive lifestyle, the bacterium …