User profiles for "author:S Sookoian"

Silvia Sookoian, MD, PhD, FAASLD.

CONICET.National Scientific and Technical Research Council - Argentina
Verified email at intramed.net
Cited by 18324

MAFLD: a consensus-driven proposed nomenclature for metabolic associated fatty liver disease

…, R Jalan, R Bataller, R Loomba, S Sookoian… - Gastroenterology, 2020 - Elsevier
Fatty liver associated with metabolic dysfunction is common, affects a quarter of the
population, and has no approved drug therapy. Although pharmacotherapies are in …

[HTML][HTML] A multisociety Delphi consensus statement on new fatty liver disease nomenclature

ME Rinella, JV Lazarus, V Ratziu, SM Francque… - Hepatology, 2023 - journals.lww.com
The principal limitations of the terms NAFLD and NASH are the reliance on exclusionary
confounder terms and the use of potentially stigmatising language. This study set out to …

Nonalcoholic fatty liver disease

…, VWS Wong, V Nobili, CP Day, S Sookoian… - Nature reviews Disease …, 2015 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a disorder characterized by excess accumulation
of fat in hepatocytes (nonalcoholic fatty liver (NAFL)); in up to 40% of individuals, there are …

Meta‐analysis of the influence of I148M variant of patatin‐like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of …

S Sookoian, CJ Pirola - Hepatology, 2011 - Wiley Online Library
Our objective was to estimate the strength of the effect of the I148M (rs738409 C/G) patatin‐
like phospholipase domain containing 3 (PNPLA3) variant on nonalcoholic fatty liver …

Noninvasive biomarkers in NAFLD and NASH—current progress and future promise

…, V de Lédinghen, GLH Wong, S Sookoian - Nature reviews …, 2018 - nature.com
Nonalcoholic fatty liver disease (NAFLD) affects 25% of the global adult population and is
the most common chronic liver disease worldwide. Nonalcoholic steatohepatitis (NASH) is …

Effects of rotating shift work on biomarkers of metabolic syndrome and inflammation

S Sookoian, C Gemma… - Journal of internal …, 2007 - Wiley Online Library
Objective. The major function of the circadian system is the internal cycling of physiological
and metabolic events. The present study sought to explore the effect of rotating shift work …

Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: a systematic review

S Sookoian, CJ Pirola - Journal of hepatology, 2008 - Elsevier
BACKGROUND/AIMS: To perform a systematic review of the studies addressing the
association between non-alcoholic fatty liver disease (NAFLD) and carotid intima-media …

Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis

…, D Flichman, F Mirshahi, AJ Sanyal, S Sookoian - Gut, 2015 - gut.bmj.com
Objectives We used a screening strategy of global serum microRNA (miRNA) profiling,
followed by a second stage of independent replication and exploration of liver expression of …

[HTML][HTML] A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

S Sookoian, GO Castaño, AL Burgueño… - Journal of lipid …, 2009 - ASBMB
We explored the role of the adiponutrin (PNPLA3) nonsynonymous-rs738409 single
nucleotide polymorphism (SNP) in genetic susceptibility to nonalcoholic fatty liver disease …

[PDF][PDF] Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: Impact of liver methylation of the peroxisome proliferator–activated receptor γ …

S Sookoian, MS Rosselli, C Gemma, AL Burgueño… - …, 2010 - Wiley Online Library
Insulin resistance (IR) and mitochondrial dysfunction play a central role in the
pathophysiology of nonalcoholic fatty liver disease (NAFLD). We hypothesized that genetic …