Lung cancer mortality reduction by LDCT screening—results from the randomized German LUSI trial

N Becker, E Motsch, A Trotter… - … journal of cancer, 2020 - Wiley Online Library
In 2011, the US National Lung Cancer Screening Trial (NLST) reported a 20% reduction of
lung cancer mortality after regular screening by low‐dose computed tomography (LDCT), as …

Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis

J Mayerle, H Kalthoff, R Reszka, B Kamlage, E Peter… - Gut, 2018 - gut.bmj.com
Objective Current non-invasive diagnostic tests can distinguish between pancreatic cancer
(pancreatic ductal adenocarcinoma (PDAC)) and chronic pancreatitis (CP) in only about two …

Prediagnostic plasma bile acid levels and colon cancer risk: a prospective study

T Kühn, M Stepien, M López-Nogueroles… - JNCI: Journal of the …, 2020 - academic.oup.com
Background Bile acids have been proposed to promote colon carcinogenesis. However,
there are limited prospective data on circulating bile acid levels and colon cancer risk in …

[HTML][HTML] Integration of tissue metabolomics, transcriptomics and immunohistochemistry reveals ERG-and gleason score-specific metabolomic alterations in prostate …

S Meller, HA Meyer, B Bethan, D Dietrich… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Integrated analysis of metabolomics, transcriptomics and immunohistochemistry can
contribute to a deeper understanding of biological processes altered in cancer and possibly …

Evaluation of prediction models for identifying malignancy in pulmonary nodules detected via low-dose computed tomography

SG Maldonado, S Delorme, A Hüsing… - JAMA Network …, 2020 - jamanetwork.com
Importance Malignancy prediction models based on participant-related characteristics and
imaging parameters from low-dose computed tomography (CT) may improve decision …

Serologic markers of Chlamydia trachomatis and other sexually transmitted infections and subsequent ovarian cancer risk: Results from the EPIC cohort

A Idahl, C Le Cornet… - … journal of cancer, 2020 - Wiley Online Library
A substantial proportion of epithelial ovarian cancer (EOC) arises in the fallopian tube and
other epithelia of the upper genital tract; these epithelia may incur damage and neoplastic …

[HTML][HTML] Impact of prolonged blood incubation and extended serum storage at room temperature on the human serum metabolome

B Kamlage, S Neuber, B Bethan… - Metabolites, 2018 - mdpi.com
Metabolomics is a powerful technology with broad applications in life science that, like other-
omics approaches, requires high-quality samples to achieve reliable results and ensure …

[HTML][HTML] Buffy coat signatures of breast cancer risk in a prospective cohort study

FFL Chung, SG Maldonado, A Nemc, L Bouaoun… - Clinical …, 2023 - Springer
Background Epigenetic alterations are a near-universal feature of human malignancy and
have been detected in malignant cells as well as in easily accessible specimens such as …

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure

OJ Müller, MB Heckmann, L Ding, K Rapti… - Cardiovascular …, 2019 - academic.oup.com
Aims Heart failure is characterized by structural and metabolic cardiac remodelling. The aim
of the present study is to expand our understanding of the complex metabolic alterations in …

[HTML][HTML] Adherence and dietary composition during intermittent vs. continuous calorie restriction: follow-up data from a randomized controlled trial in adults with …

ST Pannen, SG Maldonado, T Nonnenmacher… - Nutrients, 2021 - mdpi.com
Although intermittent calorie restriction (ICR) has become popular as an alternative weight
loss strategy to continuous calorie restriction (CCR), there is insufficient evidence on diet …