Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells
representing the interface between blood cells on the one side and hepatocytes and hepatic …

Myofibroblasts combine the matrix-producing functions of fibroblasts and the contractile
properties of smooth muscle cells. They are the main effectors of fibrosis in all tissues and …

Microvesicles (MVs) are extracellular vesicles released by virtually all cells, under both
physiological and pathological conditions. They contain lipids, proteins, RNAs and …

Background Patients with primary biliary cholangitis who have an inadequate response to
therapy with ursodeoxycholic acid are at high risk for disease progression. Fibrates, which …

Objective Patients with primary sclerosing cholangitis (PSC) were previously shown to
display a bacterial gut dysbiosis but fungal microbiota has never been examined in these …

Magnetic resonance imaging (MRI) with magnetic resonance cholangiography (MRC) has
become the radiologic standard of reference for diagnosis of primary sclerosing cholangitis …

Liver fibrosis expanding from portal tracts and vascular remodeling are determinant factors
in the progression of liver diseases to cirrhosis. In the present study, we examined the …

Portal fibroblasts with mesenchymal stem cell features form... : Hepatology Portal fibroblasts with
mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis …

Chronic liver diseases with different etiologies represent a major public health issue
worldwide. Liver fibrosis is the common feature of almost all chronic liver diseases and …

Background & Aims Primary sclerosing cholangitis (PSC) has a variable, often progressive,
course. Magnetic resonance cholangiography (MRC) is used in the diagnosis of PSC …