User profiles for "author:Sei Higuchi"

Sei Higuchi

St. John's University
Verified email at stjohns.edu
Cited by 794

Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice

K Hayakawa, T Nakano, K Irie… - Journal of Cerebral …, 2010 - journals.sagepub.com
Glial scarring is traditionally thought to be detrimental after stroke. But emerging studies now
suggest that reactive astrocytes may also contribute to neurovascular remodeling. Here, we …

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion

M Fujioka, K Hayakawa, K Mishima… - Blood, The Journal …, 2010 - ashpublications.org
Reperfusion after brain ischemia causes thrombus formation and microcirculatory
disturbances, which are dependent on the platelet glycoprotein Ib–von Willebrand factor …

Generation of fractal patterns for probing the visual memory

Y Miyashita, SI Higuchi, K Sakai, N Masui - Neuroscience research, 1991 - Elsevier
The effective use of computer-generated pictures as a trial-unique probe for studying the
visual memory is described. The shape of the pattern is determined by means of a fractal …

Dipeptidyl peptidase‐4 inhibitor anagliptin prevents intracranial aneurysm growth by suppressing macrophage infiltration and activation

T Ikedo, M Minami, H Kataoka, K Hayashi… - Journal of the …, 2017 - Am Heart Assoc
Background Chronic inflammation plays a key role in the pathogenesis of intracranial
aneurysms (IA s). DPP‐4 (dipeptidyl peptidase‐4) inhibitors have anti‐inflammatory effects …

Bile acid composition regulates GPR119-dependent intestinal lipid sensing and food intake regulation in mice

S Higuchi, TR Ahmad, DA Argueta, PA Perez, C Zhao… - Gut, 2020 - gut.bmj.com
Objectives Lipid mediators in the GI tract regulate satiation and satiety. Bile acids (BAs)
regulate the absorption and metabolism of dietary lipid in the intestine, but their effects on …

Effects of oral administration of furosemide and torsemide in healthy dogs

Y Hori, F Takusagawa, H Ikadai, M Uechi… - American journal of …, 2007 - Am Vet Med Assoc
Objective—To investigate the diuretic effects, tolerability, and adverse effects of furosemide
and torsemide after short-and long-term administration in healthy dogs. Animals—8 mixed …

Unexplained reciprocal regulation of diabetes and lipoproteins

S Higuchi, MC Izquierdo… - Current opinion in …, 2018 - journals.lww.com
Unexplained reciprocal regulation of diabetes and lipoprotei... : Current Opinion in
Lipidology Unexplained reciprocal regulation of diabetes and lipoproteins : Current Opinion …

[HTML][HTML] The prostaglandin E2 receptor EP4 regulates obesity-related inflammation and insulin sensitivity

M Yasui, Y Tamura, M Minami, S Higuchi, R Fujikawa… - PLoS …, 2015 - journals.plos.org
With increasing body weight, macrophages accumulate in adipose tissue. There, activated
macrophages secrete numerous proinflammatory cytokines and chemokines, giving rise to …

UV LED operation lifetime and radiation hardness qualification for space flights

KX Sun, N Leindecker, S Higuchi… - Journal of Physics …, 2009 - iopscience.iop.org
We report measurements of ultraviolet light emitting diode (UV LED) performance under
conditions simulating operation in an orbiting satellite. UV LED light output maintained …

Therapeutic time window of cannabidiol treatment on delayed ischemic damage via high-mobility group box1-inhibiting mechanism

K Hayakawa, K Irie, K Sano, T Watanabe… - Biological and …, 2009 - jstage.jst.go.jp
MATERIALS AND METHODS Animals Male ddY mice (25—35 g, Kiwa Experimental Animal
Laboratory, Wakayama, Japan) were kept under a 12-h light/dark cycle (lights on from 07: 00 …