Lectin-carbohydrate interactions: different folds, common recognition principles
S Elgavish, B Shaanan - Trends in biochemical sciences, 1997 - cell.com
Lectins can be found in many organisms and are involved in a multitude of cellular
processes that depend on specific recognition of complex carbohydrates. The …
processes that depend on specific recognition of complex carbohydrates. The …
Molecular and phylogenetic analyses reveal mammalian-like clockwork in the honey bee (Apis mellifera) and shed new light on the molecular evolution of the …
EB Rubin, Y Shemesh, M Cohen, S Elgavish… - Genome …, 2006 - genome.cshlp.org
The circadian clock of the honey bee is implicated in ecologically relevant complex
behaviors. These include time sensing, time-compensated sun-compass navigation, and …
behaviors. These include time sensing, time-compensated sun-compass navigation, and …
Long noncoding RNA MALAT1 promotes hepatocellular carcinoma development by SRSF1 upregulation and mTOR activation
Several long noncoding RNAs (lncRNA) are abrogated in cancer but their precise
contributions to oncogenesis are still emerging. Here we report that the lncRNA MALAT1 is …
contributions to oncogenesis are still emerging. Here we report that the lncRNA MALAT1 is …
[HTML][HTML] Single-cell transcriptomes of pancreatic preinvasive lesions and cancer reveal acinar metaplastic cells' heterogeneity
Y Schlesinger, O Yosefov-Levi, D Kolodkin-Gal… - Nature …, 2020 - nature.com
Acinar metaplasia is an initial step in a series of events that can lead to pancreatic cancer.
Here we perform single-cell RNA-sequencing of mouse pancreas during the progression …
Here we perform single-cell RNA-sequencing of mouse pancreas during the progression …
Human Nasal and Lung Tissues Infected Ex Vivo with SARS-CoV-2 Provide Insights into Differential Tissue-Specific and Virus-Specific Innate Immune Responses in …
O Alfi, A Yakirevitch, O Wald, O Wandel, U Izhar… - Journal of …, 2021 - Am Soc Microbiol
The nasal mucosa constitutes the primary entry site for respiratory viruses, including severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While the imbalanced innate …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While the imbalanced innate …
Zika virus infects early-and midgestation human maternal decidual tissues, inducing distinct innate tissue responses in the maternal-fetal interface
Y Weisblum, E Oiknine-Djian, OM Vorontsov… - Journal of …, 2017 - Am Soc Microbiol
Zika virus (ZIKV) has emerged as a cause of congenital brain anomalies and a range of
placenta-related abnormalities, highlighting the need to unveil the modes of maternal-fetal …
placenta-related abnormalities, highlighting the need to unveil the modes of maternal-fetal …
[HTML][HTML] Site-directed mutagenesis, proteolytic cleavage, and activation of human proheparanase
G Abboud-Jarrous, Z Rangini-Guetta, H Aingorn… - Journal of Biological …, 2005 - ASBMB
Heparanase is an endo-β-d-glucuronidase that degrades heparan sulfate in the
extracellular matrix and cell surfaces. Human proheparanase is produced as a latent 65-kDa …
extracellular matrix and cell surfaces. Human proheparanase is produced as a latent 65-kDa …
Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling
N Rosenberg, M Van Haele, T Lanton, N Brashi… - Journal of …, 2022 - Elsevier
Background & Aims Primary liver cancers include hepatocellular carcinoma (HCC),
intrahepatic cholangiocarcinoma (CCA) and combined HCC-CCA tumors (cHCC-CCA). It …
intrahepatic cholangiocarcinoma (CCA) and combined HCC-CCA tumors (cHCC-CCA). It …
The genetic program of pancreatic β-cell replication in vivo
A Klochendler, I Caspi, N Corem, M Moran… - Diabetes, 2016 - Am Diabetes Assoc
The molecular program underlying infrequent replication of pancreatic β-cells remains
largely inaccessible. Using transgenic mice expressing green fluorescent protein in cycling …
largely inaccessible. Using transgenic mice expressing green fluorescent protein in cycling …
[HTML][HTML] Two regions in the N-terminal domain of ionotropic glutamate receptor 3 form the subunit oligomerization interfaces that control subtype-specific receptor …
G Ayalon, E Segev, S Elgavish, Y Stern-Bach - Journal of Biological …, 2005 - ASBMB
The N-terminal domain (NTD) of α-amino-3-hydroxy-5-methylisoxazolepropionate (AMPA)
and kainate glutamate receptors plays an important role in controlling subtype specific …
and kainate glutamate receptors plays an important role in controlling subtype specific …