Gene regulation in the magnocellular hypothalamo-neurohypophysial system
JPH Burbach, SM Luckman, D Murphy… - Physiological …, 2001 - journals.physiology.org
The hypothalamo-neurohypophysial system (HNS) is the major peptidergic neurosecretory
system through which the brain controls peripheral physiology. The hormones vasopressin …
system through which the brain controls peripheral physiology. The hormones vasopressin …
Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity
The close correspondence between energy intake and expenditure over prolonged time
periods, coupled with an apparent protection of the level of body adiposity in the face of …
periods, coupled with an apparent protection of the level of body adiposity in the face of …
Glucose-sensing neurons of the hypothalamus
D Burdakov, SM Luckman… - … Transactions of the …, 2005 - royalsocietypublishing.org
Specialized subgroups of hypothalamic neurons exhibit specific excitatory or inhibitory
electrical responses to changes in extracellular levels of glucose. Glucose-excited neurons …
electrical responses to changes in extracellular levels of glucose. Glucose-excited neurons …
Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers
CB Lawrence, AC Snape, FMH Baudoin… - …, 2002 - academic.oup.com
Ghrelin was recently identified as the endogenous ligand for the GH secretagogue (GHS)
receptor. Like the synthetic GHSs [eg GH-releasing peptide-6 (GHRP-6)], ghrelin stimulates …
receptor. Like the synthetic GHSs [eg GH-releasing peptide-6 (GHRP-6)], ghrelin stimulates …
Induction of c-fos Messenger Ribonucleic Acid in Neuropeptide Y and Growth Hormone (GH)-Releasing Factor Neurons in the Rat Arcuate Nucleus Following …
SL Dickson, SM Luckman - Endocrinology, 1997 - academic.oup.com
In this study we investigated the neurochemical identity of the arcuate cells activated
following GH-releasing peptide-6 (GHRP-6) injection by comparing, on consecutive …
following GH-releasing peptide-6 (GHRP-6) injection by comparing, on consecutive …
Alternative role for prolactin-releasing peptide in the regulation of food intake
CB Lawrence, F Celsi, J Brennand… - Nature neuroscience, 2000 - nature.com
Prolactin-releasing peptide (PrRP) is a peptide ligand for the human orphan G-protein-
coupled receptor hGR3/GPR10 and causes the secretion of prolactin from anterior pituitary …
coupled receptor hGR3/GPR10 and causes the secretion of prolactin from anterior pituitary …
Induction of c-fos expression in hypothalamic magnocellular neurons requires synaptic activation and not simply increased spike activity
SM Luckman, RE Dyball, G Leng - Journal of Neuroscience, 1994 - Soc Neuroscience
Magnocellular neurons of the hypothalamic supraoptic nucleus have been shown to express
the immediate-early gene c-fos in a number of experimental and physiological …
the immediate-early gene c-fos in a number of experimental and physiological …
PRL-releasing peptide reduces food intake and may mediate satiety signaling
CB Lawrence, KLJ Ellacott, SM Luckman - Endocrinology, 2002 - academic.oup.com
PRL-releasing peptide (PrRP) administered centrally inhibits food intake and body weight
gain. To elucidate the role of PrRP, its actions were compared with those of a homeostatic …
gain. To elucidate the role of PrRP, its actions were compared with those of a homeostatic …
[HTML][HTML] The role of RFamide peptides in feeding
DA Bechtold, SM Luckman - Journal of endocrinology, 2007 - joe.bioscientifica.com
In the three decades since FMRFamide was isolated from the clam Macrocallista nimbosa,
the list of RFamide peptides has been steadily growing. These peptides occur widely across …
the list of RFamide peptides has been steadily growing. These peptides occur widely across …
[HTML][HTML] The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus
GT Dodd, AA Worth, N Nunn, AK Korpal, DA Bechtold… - Cell metabolism, 2014 - cell.com
Leptin is a critical regulator of metabolism, which acts on brain receptors (Lepr) to reduce
energy intake and increase energy expenditure. Some of the cellular pathways mediating …
energy intake and increase energy expenditure. Some of the cellular pathways mediating …