Abstract In December 1997, the National Cancer Institute sponsored “The International
Workshop on Microsatellite Instability and RER Phenotypes in Cancer Detection and …

MicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …

The incidence of adenocarcinoma of the esophagus has been increasing in developing
countries over the last three decades and probably reflects a genuine increase in the …

Germ-line mutations in the tumor suppressor gene APC are associated with hereditary
familial adenomatous polyposis (FAP), and somatic mutations are common in sporadic …

We assess toxicity related to 6-mercaptopurine in the treatment of inflammatory bowel
disease by reporting our experience with 396 patients (120 patients with ulcerative colitis …

BACKGROUND & AIMS: Esophageal adenocarcinoma (EA) is increasingly common among
patients with Barrett's esophagus (BE). We aimed to provide consensus recommendations …

Barrett's esophagus is a premalignant condition arising in response to chronic reflux
esophagitis. Inducible nitric oxide synthase (iNOS; NOS-2) and cyclooxygenase-2 (COX-2) …

Abstract Background: E (epithelial)-cadherin, the cell adhesion molecule also considered a
potential invasion/metastasis suppressor, is mutationally inactivated in nearly half of all …

Human gastric carcinoma shows a higher prevalence of microsatellite instability (MSI) than
does any other type of sporadic human cancer. The reasons for this high frequency of MSI …

Most of the studies characterizing DNA methylation patterns have been restricted to
particular genomic loci in a limited number of human samples and pathological conditions …