Human visceral leishmaniasis (HVL) is the most severe clinical form of a spectrum of
neglected tropical diseases caused by protozoan parasites of the genus Leishmania …

High genetic diversity is a hallmark of the gastric pathogen Helicobacter pylori. We used 454
sequencing technology to perform whole-genome comparisons for five sets of H. pylori …

Representative data on the extent of endemicity, burden and risk of human toxoplasmosis
are scarce. We assessed the prevalence and determinants of seropositivity of Toxoplasma …

NF-κB/Rel transcription factors and IκB kinases (IKK) are essential for inflammation and
immune responses, but also for bone-morphogenesis, skin proliferation and differentiation …

Possibilities to study the biology of human protozoan parasites and their interaction with the
host remain severely limited, either because of non-existent or inappropriate animal models …

Background: Helicobacter pylori remains a global health hazard, and vaccination would be
ideal for its control. Natural infection appears not to induce protective immunity. Thus, the …

Leishmania spp. cause a wide spectrum of tropical diseases which are threatening an
estimated 350 million people around the globe. While in most cases non-fatal, the disease is …

Abstract The Gram negative bacterium Helicobacter pylori is a human pathogen which
infects the gastric mucosa and causes an inflammatory process leading to gastritis …

Helicobacter pylori may cause chronic gastritis, gastric cancer, or lymphoma. Myeloid
antigen-presenting cells (APCs) are most likely involved in the induction and expression of …

Background Giardia duodenalis is highly endemic in East Africa but its effects on child
health, particularly of submicroscopic infections, ie, those below the threshold of microscopy …