The intestinal microbiota fuelling metabolic inflammation
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …
Gut-liver axis: Pathophysiological concepts and clinical implications
H Tilg, TE Adolph, M Trauner - Cell Metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
[PDF][PDF] The intestinal microbiota in colorectal cancer
Experimental evidence from the past years highlights a key role for the intestinal microbiota
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Paneth cells as a site of origin for intestinal inflammation
TE Adolph, MF Tomczak, L Niederreiter, HJ Ko, J Böck… - Nature, 2013 - nature.com
The recognition of autophagy related 16-like 1 (ATG16L1) as a genetic risk factor has
exposed the critical role of autophagy in Crohn's disease. Homozygosity for the highly …
exposed the critical role of autophagy in Crohn's disease. Homozygosity for the highly …
Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity
Non-alcoholic fatty liver disease (NAFLD) has emerged pandemically across the globe and
particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic …
particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic …
Calprotectin: from biomarker to biological function
The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …
Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liver disease
C Grander, TE Adolph, V Wieser, P Lowe, L Wrzosek… - Gut, 2018 - gut.bmj.com
Objective Alcoholic liver disease (ALD) is a global health problem with limited therapeutic
options. Intestinal barrier integrity and the microbiota modulate susceptibility to ALD …
options. Intestinal barrier integrity and the microbiota modulate susceptibility to ALD …
Postacute COVID-19 is characterized by gut viral antigen persistence in inflammatory bowel diseases
A Zollner, R Koch, A Jukic, A Pfister, M Meyer… - Gastroenterology, 2022 - Elsevier
Background & Aims The coronavirus disease 2019 (COVID-19) pandemic has affected
populations, societies, and lives for more than 2 years. Long-term sequelae of COVID-19 …
populations, societies, and lives for more than 2 years. Long-term sequelae of COVID-19 …
[HTML][HTML] Multiple parallel hits hypothesis in nonalcoholic fatty liver disease: revisited after a decade
H Tilg, TE Adolph, AR Moschen - Hepatology, 2021 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is an epidemic liver disease, affecting
approximately one quarter of the entire population in the world.(1) This disease …
approximately one quarter of the entire population in the world.(1) This disease …