User profiles for "author:Timothy Zaki"

Timothy Zaki

David Geffen School of Medicine at UCLA
Verified email at mednet.ucla.edu
Cited by 203

Changing epidemiology of colorectal cancer—birth cohort effects and emerging risk factors

CC Murphy, TA Zaki - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Incidence and mortality of colorectal cancer (CRC) are increasing worldwide, suggesting
broad changes in the epidemiology of CRC. In this Review, we discuss the changes that are …

Racial and ethnic disparities in early-onset colorectal cancer survival

TA Zaki, PS Liang, FP May, CC Murphy - Clinical Gastroenterology and …, 2023 - Elsevier
Background Young adults diagnosed with colorectal cancer (CRC) comprise a growing, yet
understudied, patient population. We estimated 5-year relative survival of early-onset CRC …

Maternal obesity, pregnancy weight gain, and birth weight and risk of colorectal cancer

CC Murphy, PM Cirillo, NY Krigbaum, AG Singal… - Gut, 2022 - gut.bmj.com
Objective Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide.
Obesity is a well-established risk factor for CRC, and fetal or developmental origins of …

A comparison of levetiracetam and phenobarbital for the treatment of neonatal seizures associated with hypoxic–ischemic encephalopathy

LM Rao, SA Hussain, T Zaki, A Cho, T Chanlaw… - Epilepsy & Behavior, 2018 - Elsevier
Purpose Seizures are common in term infants with hypoxic–ischemic encephalopathy (HIE)
undergoing therapeutic hypothermia. Although phenobarbital (PHB) is generally considered …

Risk of hepatocellular carcinoma in patients with indeterminate (LI-RADS 3) liver observations

A Arvind, S Joshi, T Zaki, D Burkholder… - Clinical …, 2023 - cghjournal.org
Early hepatocellular cancer (HCC) detection is associated with curative treatment and
improved survival. 1 The American Association for the Study of Liver Diseases recommends …

In-utero exposure to antibiotics and risk of colorectal cancer in a prospective cohort of 18 000 adult offspring

CC Murphy, PM Cirillo, NY Krigbaum… - International Journal …, 2023 - academic.oup.com
Background Incidence rates of colorectal cancer (CRC) are increasing among younger
adults and in mid-life, implicating exposures in early life as risk factors. We examined the …

Increasing incidence rates of colorectal cancer at ages 50–54 years

TA Zaki, AG Singal, FP May, CC Murphy - Gastroenterology, 2022 - gastrojournal.org
Several studies have demonstrated that incidence rates of early-onset CRC have increased
successively across generations. 1, 2 Persons born in and after the 1950s and 1960s, now …

[PDF][PDF] Colorectal cancer in younger adults

P Dharwadkar, TA Zaki, CC Murphy - Hematology/oncology clinics of North …, 2022 - Elsevier
Colorectal cancer (CRC) is a major cause of cancer-related morbidity and mortality in the
United States. The incidence and mortality rates have decreased in adults aged older than …

Declines in colorectal cancer incidence and mortality rates slow among older adults

CC Murphy, JK Lee, PS Liang, FP May… - Clinical Gastroenterology …, 2024 - Elsevier
Disclosures: Dr. Murphy reports consulting for Freenome. Dr. Liang reports research support
from Epigenomics and Freenome and serving on the advisory board of Guardant Health. Dr …

Survival of Middle Eastern and North African Individuals Diagnosed with Colorectal Cancer: A Population-Based Study in California

TA Zaki, A Ziogas, J Chang, CC Murphy… - … Biomarkers & Prevention, 2023 - AACR
Background: Literature on colorectal cancer outcomes in individuals of Middle Eastern and
North African (MENA) descent is limited. To address this gap, we estimated five-year …