Vegetables of the Allium genus, such as garlic (Allium sativum L.), onions, shallots, leaks,
and chives, have been used for many years for food consumption and for medicinal …

There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

Cancer metabolism has been studied for years and adopted in the clinic for monitoring
disease progression and therapy response. Despite our growing knowledge of a distinctly …

Targetable drivers governing 5-fluorouracil and cisplatin (5FU+ CDDP) resistance remain
elusive due to the paucity of physiologically and therapeutically relevant models. Here, we …

Background and Aims Most tumor cells use aerobic glycolysis (the Warburg effect) to
support anabolic growth and promote tumorigenicity and drug resistance. Intriguingly, the …

The tumor microenvironment plays a critical role in maintaining the immature phenotype of
tumor-initiating cells (TIC) to promote cancer. Hepatocellular carcinoma (HCC) is a unique …

Rapidly growing tumors often experience hypoxia and nutrient (eg, glucose) deficiency
because of poor vascularization. Tumor cells respond to the cytotoxic effects of such …

Arginine methylation is a post-translational modification that plays pivotal roles in signal
transduction and gene transcription during cell fate determination. We found protein …

This paper starts by investigating Ackermann's interpretation of finite set theory in the natural
numbers. We give a formal version of this interpretation from Peano arithmetic (PA) to …

Accumulating evidence has demonstrated that drug resistance can be acquired in cancer
through the repopulation of tumors by cancer stem cell (CSC) expansion. Here, we …