Persistent symptoms in adult patients 1 year after coronavirus disease 2019 (COVID-19): a prospective cohort study

…, M Kirchner, A Lim, B Müller, U Merle - Clinical infectious …, 2022 - academic.oup.com
Background Long COVID is defined as the persistence of symptoms beyond 3 months after
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. To better …

[HTML][HTML] SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas

…, R Groß, C Conzelmann, J Krüger, U Merle… - Nature …, 2021 - nature.com
Infection-related diabetes can arise as a result of virus-associated β-cell destruction. Clinical
data suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Clinical presentation, diagnosis and long-term outcome of Wilson's disease: a cohort study

U Merle, M Schaefer, P Ferenci, W Stremmel - Gut, 2007 - gut.bmj.com
Background: Wilson's disease is a rare inborn disease related to copper storage, leading to
liver cirrhosis and neuropsychological deterioration. Clinical data on larger cohorts are …

A phase 3, randomized trial of bulevirtide in chronic hepatitis D

…, J Flaherty, A Osinusi, Y Liu, U Merle… - … England Journal of …, 2023 - Mass Medical Soc
Background Coinfection with hepatitis D virus (HDV) accelerates the progression of liver
disease associated with chronic hepatitis B. Bulevirtide inhibits the entry of HDV into …

[HTML][HTML] Vitamin D deficiency and outcome of COVID-19 patients

…, S Tiwari-Heckler, S Dreher, M Boxberger, U Merle - Nutrients, 2020 - mdpi.com
Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses an
enormous challenge to health care systems throughout the world. Without causal treatment …

Post-acute sequelae of covid-19 six to 12 months after infection: population based study

…, SO Brockmann, S Göpel, G Kindle, U Merle… - Bmj, 2022 - bmj.com
Objectives To describe symptoms and symptom clusters of post-covid syndrome six to 12
months after acute infection, describe risk factors, and examine the association of symptom …

[HTML][HTML] COVID-19 in cancer patients: clinical characteristics and outcome—an analysis of the LEOSS registry

…, N Isberner, P Köhler, J Lanznaster, U Merle… - Annals of …, 2021 - Springer
Introduction Since the early SARS-CoV-2 pandemic, cancer patients have been assumed to
be at higher risk for severe COVID-19. Here, we present an analysis of cancer patients from …

Efficacy and safety of oral chelators in treatment of patients with Wilson disease

…, M Schäfer, U Teufel, F Wiegand, U Merle… - Clinical …, 2013 - Elsevier
Background & Aims Wilson disease is a genetic copper storage disorder that causes hepatic
and neurologic symptoms. Chelating agents (D-penicillamine, trientine) are used as first-line …

[HTML][HTML] SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

…, M Gendarme, B El Debs, N Halama, U Merle… - Communications …, 2022 - nature.com
SARS-CoV-2 is a novel virus that has rapidly spread, causing a global pandemic. In the
majority of infected patients, SARS-CoV-2 leads to mild disease; however, in a significant …

[HTML][HTML] Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical …

…, J Krisam, L Baumann, J Stermann, U Merle… - Nature Cancer, 2023 - nature.com
Patients with cancer are at high risk of severe coronavirus disease 2019 (COVID-19), with
high morbidity and mortality. Furthermore, impaired humoral response renders severe acute …