Infliximab in inflammatory bowel disease: clinical outcome in a population based cohort from Stockholm County

…, PM Hellström, A Lapidus, I Janczewska, U Sjöqvist… - Gut, 2004 - gut.bmj.com
Background: Several placebo controlled studies have demonstrated the efficacy of infliximab
in inflammatory bowel disease (IBD) but the potential toxicity of this new biological …

[HTML][HTML] Capsule retentions and incomplete capsule endoscopy examinations: an analysis of 2300 examinations

…, J Gorsetman, O Broström, U Sjöqvist - … research and practice, 2011 - hindawi.com
Aim. To evaluate capsule endoscopy in terms of incomplete examinations and capsule
retentions and to find risk factors for these events. Material and Methods. This retrospective …

Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men

…, L Törkvist, M Fredrikson, U Sjöqvist… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Crohn's disease (CD) is characterized by overproduction of proinflammatory
cytokines like interleukin (IL)-1β. Production of mature IL-1β is dependent on a caspase-1 …

Ursodeoxycholic acid treatment in IBD-patients with colorectal dysplasia and/or DNA-aneuploidy: a prospective, double-blind, randomized controlled pilot study

U Sjöqvist, B Tribukait, AKE ÖST, C Einarsson… - Anticancer …, 2004 - ar.iiarjournals.org
Background & Aims: There is an increased risk of colorectal carcinoma (CRC) in patients
with longstanding, extensive colonic inflammatory bowel disease (IBD). Primary sclerosing …

Chronic colitis is associated with a reduction of mucosal alkaline sphingomyelinase activity

U Sjöqvist, E Hertervig, Å Nilsson… - Inflammatory Bowel …, 2002 - academic.oup.com
Summary Background and Aims The hydrolysis of sphingomyelin (SM) generates key
molecules regulating cell growth. Animal cancer studies support an inhibitory role for this …

Capsule endoscopic findings correlate with fecal calprotectin and C-reactive protein in patients with suspected small-bowel Crohn's disease

…, LÅ Bark, O Broström, U Sjöqvist - Scandinavian Journal of …, 2014 - Taylor & Francis
Objective. Capsule endoscopy (CE) is a sensitive method for detecting inflammatory lesions
in the small bowel. Such lesions may be due to Crohn's disease but also to other causes …

Dysplasia in ulcerative colitis—clinical consequences?

U Sjöqvist - Langenbeck's Archives of Surgery, 2004 - Springer
Background The overall absolute risk of colorectal cancer (CRC) in longstanding extensive
or total ulcerative colitis (UC) is estimated to be 10%–15%. The size of this risk is 6-to 10 …

Contribution of the NOD1/CARD4 insertion/deletion polymorphism +32656 to inflammatory bowel disease in Northern Europe#

…, G Mahdi, ID Arnott, U Sjöqvist… - Inflammatory bowel …, 2007 - academic.oup.com
Abstract Background NOD1/CARD4 and NOD2/CARD15 are both intracellular pattern-
recognition receptors. The NOD1/CARD4 gene lies within a previously described …

Contribution of CARD15 variants in determining susceptibility to Crohn's disease in Sweden

L Törkvist, CL Noble, M Lördal, U Sjöqvist… - Scandinavian journal …, 2006 - Taylor & Francis
Objective. Crohn's disease (CD) is a chronic inflammatory bowel disorder caused by
environmental and genetic factors. Mutations in the CARD15 gene have been associated …

Contribution of the IBD5 locus to Crohn's disease in the Swedish population

L Törkvist, CL Noble, M Lördal, U Sjöqvist… - Scandinavian journal …, 2007 - Taylor & Francis
Objective. Recent data have controversially suggested that variants of the organic cation
transport genes SLC22A4 (OCTN1) and SLC22A5 (OCTN2) are responsible for the …