Neuronal differentiation from neural stem cells into mature neurons is guided by the
concerted action of specific transcription factors that stepwise exercise their role in the …

The deletion of the neuronal Nap1l2 (n ucleosome a ssembly p rotein 1-l ike 2) gene in mice
causes neural tube defects. We demonstrate here that this phenotype correlates with …

Abstract Type 1 diabetes (T1D) is characterized by a chronic, progressive autoimmune
attack against pancreas-specific antigens, effecting the destruction of insulin-producing β …

Mammals possess five nucleosome assembly protein 1-like (NAP1L) proteins, with three of
them being expressed exclusively in the nervous system. The biological importance of the …

Objective Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of
pancreatic β-cells producing insulin. Both T1D patients and animal models exhibit gut …

The Idd6 murine type 1 diabetes locus has been shown to control diabetes by regulating the
protective activity of the peripheral immune system, as demonstrated by diabetes transfer …

The genetic locus Idd6 confers susceptibility to the spontaneous development of type 1
diabetes in the NOD mouse. Our studies on disease resistance of the congenic mouse strain …

The Idd6 locus on mouse chromosome 6, which controls the development of type 1 diabetes
in the NOD mouse, affects proliferation rates of T cells and the activity of regulatory CD4+ …

Our previous studies of the murine genetic locus Idd6 revealed the aryl hydrocarbon
receptor nuclear translocator‐like protein 2 (Arntl2) as a candidate gene for type 1 diabetes; …

In the nonobese diabetes mouse, the murine type 1 diabetes susceptibility locus Idd20
interacts genetically with the diabetes resistance locus Idd19. Both Idd s are located on …