User profiles for "author:Uxia Fernandez"
Uxía Fernández-Folgueiras (ORCID: 0000-0001-5535-0559)Universidad Autónoma de Madrid Verified email at uam.es Cited by 257 |
[HTML][HTML] Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis
MF Fondevila, U Fernandez, V Heras, T Parracho… - Journal of …, 2022 - Elsevier
Background & Aims The pathogenesis of liver fibrosis requires activation of hepatic stellate
cells (HSCs); once activated, HSCs lose intracellular fatty acids but the role of fatty acid …
cells (HSCs); once activated, HSCs lose intracellular fatty acids but the role of fatty acid …
[HTML][HTML] O-GlcNAcylated p53 in the liver modulates hepatic glucose production
MJ Gonzalez-Rellan, MF Fondevila… - Nature …, 2021 - nature.com
Abstract p53 regulates several signaling pathways to maintain the metabolic homeostasis of
cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes …
cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes …
[PDF][PDF] The L‐α‐Lysophosphatidylinositol/G Protein–Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis
MF Fondevila, U Fernandez, MJ Gonzalez‐Rellan… - …, 2021 - Wiley Online Library
Background and Aims G protein–coupled receptor (GPR) 55 is a putative cannabinoid
receptor, and l‐α‐lysophosphatidylinositol (LPI) is its only known endogenous ligand …
receptor, and l‐α‐lysophosphatidylinositol (LPI) is its only known endogenous ligand …
[PDF][PDF] Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism
MJ Gonzalez-Rellan, U Fernández, T Parracho… - Cell metabolism, 2023 - cell.com
Neddylation is a post-translational mechanism that adds a ubiquitin-like protein, namely
neural precursor cell expressed developmentally downregulated protein 8 (NEDD8). Here …
neural precursor cell expressed developmentally downregulated protein 8 (NEDD8). Here …
[HTML][HTML] Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
N da Silva Lima, MF Fondevila, E Nóvoa, X Buqué… - Journal of …, 2022 - Elsevier
Background & Aims Autophagy-related gene 3 (ATG3) is an enzyme mainly known for its
actions in the LC3 lipidation process, which is essential for autophagy. Whether ATG3 plays …
actions in the LC3 lipidation process, which is essential for autophagy. Whether ATG3 plays …
[HTML][HTML] Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis
B Porteiro, MF Fondevila, X Buque… - Molecular …, 2018 - Elsevier
Objective Recent reports have implicated the p53 tumor suppressor in the regulation of lipid
metabolism. We hypothesized that the pharmacological activation of p53 with low-dose …
metabolism. We hypothesized that the pharmacological activation of p53 with low-dose …
[HTML][HTML] Affective norms of 875 Spanish words for five discrete emotional categories and two emotional dimensions
JA Hinojosa, N Martínez-García… - Behavior research …, 2016 - Springer
In the present study, we introduce affective norms for a new set of Spanish words, the Madrid
Affective Database for Spanish (MADS), that were scored on two emotional dimensions …
Affective Database for Spanish (MADS), that were scored on two emotional dimensions …
[HTML][HTML] Wellbeing and Complementary Therapies in Breast Cancer Peripheral Neuropathy Care: A Scoping Review Focused on Foot Health
R Veiga-Seijo, ME Perez-Lopez, U Fernandez-Lopez… - Cancers, 2023 - mdpi.com
Simple Summary Chemotherapy-induced peripheral neuropathy is highly relevant in breast
cancer because of the symptoms it triggers and its corresponding negative impact on health …
cancer because of the symptoms it triggers and its corresponding negative impact on health …
[PDF][PDF] p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
MF Fondevila, E Novoa, MJ Gonzalez-Rellan… - Cell Reports …, 2024 - cell.com
The p63 protein has pleiotropic functions and, in the liver, participates in the progression of
nonalcoholic fatty liver disease (NAFLD). However, its functions in hepatic stellate cells …
nonalcoholic fatty liver disease (NAFLD). However, its functions in hepatic stellate cells …
HLA‐A*11:01 and HLA‐C*04:01 are associated with severe COVID‐19
P Castro‐Santos, A Rojas‐Martinez, JA Riancho… - HLA, 2023 - Wiley Online Library
We analyzed the association between HLA polymorphisms and susceptibility to SARS‐CoV‐
2 infection and disease severity. Genotyping data from a total of 9373 COVID‐19‐positive …
2 infection and disease severity. Genotyping data from a total of 9373 COVID‐19‐positive …