Objectives: To determine the clinical outcome of dietary fiber therapy in patients with chronic
constipation. Methods: One hundred, forty-nine patients with chronic constipation (age 53 yr …

Background: Wireless capsule endoscopy (WCE) offers endoscopic access to the small
bowel and may therefore change diagnostic and therapeutic strategies in small bowel …

OBJECTIVES: This study was designed to evaluate whether detailed symptom analysis
would help to identify pathophysiologic subgroups in chronic constipation. METHODS: In …

We challenged the two hypotheses: first, that defecation can be suppressed for an extended
time, and second, if so, that this has an effect on upper colonic motility. Thus we studied 12 …

Results: The patients included in the study had obscure gastrointestinal bleeding (n= 8),
Crohn's disease (n= 8), unexplained diarrhea (n= 5), or suspected carcinoid tumor (n= 1) …

Objective: Previous studies in patients with chronic constipation found abnormalities in the
nervous tissue of the large intestine, predominantly in the muscularis externa. Since there is …

BACKGROUND: In the absence of oesophageal erosions longterm pH monitoring is the
present gold standard for diagnosing gastro-oesophageal reflux disease (GORD). This …

Abstract Background and Study Aims: At many centers wireless capsule endoscopy (WCE)
without prior radiographic examination to rule out relevant strictures is considered to be …

Background: In the absence of highly specific symptoms and without esophageal erosions,
long-term pH monitoring is necessary for diagnosing gastroesophageal reflux disease. This …

Background—Anismus is thought to be a cause of chronic constipation by producing outlet
obstruction. The underlying mechanism is paradoxical contraction of the anal sphincter or …