Abstract Although 5-methylcytosine (m5C) is a widespread modification in RNAs, its
regulation and biological role in pathological conditions (such as cancer) remain unknown …

Background Immunotherapy with immune checkpoint inhibitors combined with an anti-
angiogenic tyrosine-kinase inhibitor (TKI) has been shown to improve overall survival versus …

Abstract Purpose: Circular RNAs (circRNAs), a novel class of noncoding RNAs, have
recently drawn lots of attention in the pathogenesis of human cancers. However, the role of …

The incidence and prevalence of inflammatory bowel disease have been increasing for
decades and IBD has become a worldwide disease. Epidemiology studies demonstrated …

Abstract Background & Aims Oral antiviral therapy may reduce the disease progression of
chronic hepatitis B (CHB) patients. We aimed to further investigate the efficacy of long‐term …

Circadian rhythm plays an important role in the regulation of digestive system. The human
circadian rhythm is controlled by at least nine circadian genes. The aims of this study are to …

BACKGROUND & AIMS: Dual chronic infection with hepatitis C virus (HCV) and hepatitis B
virus (HBV) is common in areas endemic for either virus. Combination therapy with ribavirin …

Highlights• Yarrowia has shown the potential for producing complex terpenoids.• Yarrowia
may hold multiple cytosolic acetyl-CoA and NADPH generation pathways.• Metabolite …

Etiological variations in hepatocellular carcinoma (HCC) exist across different geographic
areas. To gain better control of HCC, we retrospectively studied the secular trends and …

PURPOSE: To evaluate peripheral vascular endothelial function in patients with normal-
tension glaucoma (NTG) and primary open-angle glaucoma (POAG) using noninvasive …