[HTML][HTML] Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis
Circular RNAs (circRNAs) are recently identified as a naturally occurring family of
widespread and diverse endogenous noncoding RNAs that may regulate gene expression …
widespread and diverse endogenous noncoding RNAs that may regulate gene expression …
[HTML][HTML] Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs
Circular RNAs (circRNAs) represent a class of widespread and diverse endogenous RNAs
that may regulate gene expression in eukaryotes. However, the regulation and function of …
that may regulate gene expression in eukaryotes. However, the regulation and function of …
[HTML][HTML] IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway
TNFα has recently emerged as a regulator linking inflammation to cancer pathogenesis, but
the detailed cellular and molecular mechanisms underlying this link remain to be elucidated …
the detailed cellular and molecular mechanisms underlying this link remain to be elucidated …
Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer
Circular RNAs (circRNAs) comprise a novel class of widespread non-coding RNAs that may
regulate gene expression in eukaryotes. However, the characterization and function of …
regulate gene expression in eukaryotes. However, the characterization and function of …
Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region
S Wu, S Huang, J Ding, Y Zhao, L Liang, T Liu, R Zhan… - Oncogene, 2010 - nature.com
Cyclin-dependent kinase inhibitor 1A (CDKN1A), also known as p21Cip1/Waf1, is a master
downstream effector of tumor suppressors. In this study, we experimentally demonstrate …
downstream effector of tumor suppressors. In this study, we experimentally demonstrate …
Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization
Apoptosis is critical for embryonic development, tissue homeostasis, and tumorigenesis and
is determined largely by the Bcl-2 family of antiapoptotic and prosurvival regulators. Here …
is determined largely by the Bcl-2 family of antiapoptotic and prosurvival regulators. Here …
exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes
Exosomes, which are nanosized endocytic vesicles that are secreted by most cells, contain
an abundant cargo of different RNA species that can modulate the behavior of recipient cells …
an abundant cargo of different RNA species that can modulate the behavior of recipient cells …
Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA
J Ding, S Huang, S Wu, Y Zhao, L Liang, M Yan… - Nature cell …, 2010 - nature.com
Recurrent chromosomal aberrations are often observed in hepatocellular carcinoma (HCC),
but little is known about the functional non-coding sequences, particularly microRNAs …
but little is known about the functional non-coding sequences, particularly microRNAs …
Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma
MicroRNAs (miRNAs) are important gene regulators, which are often deregulated in
cancers. In this study, the authors analyzed the microRNAs profiles of 78 matched …
cancers. In this study, the authors analyzed the microRNAs profiles of 78 matched …
MicroRNA-148a Suppresses Tumor Cell Invasion and Metastasis by Downregulating ROCK1 in Gastric Cancer
Purpose: MicroRNAs (miRNA) have been documented playing a critical role in cancer
development and progression. In this study, we investigate the role of miR-148a in gastric …
development and progression. In this study, we investigate the role of miR-148a in gastric …