[HTML][HTML] Triple-negative breast cancer molecular subtyping and treatment progress

L Yin, JJ Duan, XW Bian, S Yu - Breast Cancer Research, 2020 - Springer
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not
express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth …

Metal-organic frameworks-based nanozymes for combined cancer therapy

S Ding, L He, X Bian, G Tian - Nano Today, 2020 - Elsevier
Nanomaterials with enzyme-like catalytic activity, named as nanozymes, have aroused wide
research interest owing to their striking merits bridging nanotechnology and biology. Metal …

Nanoscaled metal‐organic frameworks for biosensing, imaging, and cancer therapy

J Zhou, G Tian, L Zeng, X Song… - Advanced Healthcare …, 2018 - Wiley Online Library
Owing to the progressive development of metal‐organic frameworks (MOFs) synthetic
processes and their unique characters associated with the excellent performance …

[PDF][PDF] COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas

X Ren, W Wen, X Fan, W Hou, B Su, P Cai, J Li, Y Liu… - Cell, 2021 - cell.com
A dysfunctional immune response in coronavirus disease 2019 (COVID-19) patients is a
recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent …

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction

X Liu, Y Wang, H Lu, J Li, X Yan, M Xiao, J Hao… - Nature, 2019 - nature.com
T cells become dysfunctional when they encounter self antigens or are exposed to chronic
infection or to the tumour microenvironment 1. The function of T cells is tightly regulated by a …

[HTML][HTML] Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients

C Wang, J Xie, L Zhao, X Fei, H Zhang, Y Tan, X Nie… - …, 2020 - thelancet.com
Background The novel coronavirus pneumonia COVID-19 caused by SARS-CoV-2 infection
could lead to a series of clinical symptoms and severe illnesses, including acute respiratory …

[HTML][HTML] A single-cell transcriptomic landscape of the lungs of patients with COVID-19

S Wang, X Yao, S Ma, Y Ping, Y Fan, S Sun, Z He… - Nature cell …, 2021 - nature.com
The lung is the primary organ targeted by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), making respiratory failure a leading coronavirus disease 2019 (COVID-19) …

Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway

X Ye, S Xu, Y Xin, S Yu, Y Ping, L Chen… - The Journal of …, 2012 - journals.aai.org
The invasion of malignant glioma cells into the surrounding normal brain tissues is crucial
for causing the poor outcome of this tumor type. Recent studies suggest that glioma stem …

[HTML][HTML] A cohort autopsy study defines COVID-19 systemic pathogenesis

XH Yao, T Luo, Y Shi, ZC He, R Tang, PP Zhang, J Cai… - Cell research, 2021 - nature.com
Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by
dysfunction of the lungs and extrapulmonary organs. However, the organotropism of SARS …

The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2

F Zheng, YJ Liao, MY Cai, YH Liu, TH Liu, SP Chen… - Gut, 2012 - gut.bmj.com
Background Recent profile studies of microRNA (miRNA) expression have documented a
deregulation of miRNA (miR-124) in hepatocellular carcinoma (HCC). Objective To …