Background Patients with type 2 diabetes mellitus are at increased risk of cardiovascular
disease, partly owing to dyslipidaemia, which can be amenable to fibrate therapy. We …

Background Hyperlipidemia has been suggested as a risk factor for stenosis of the aortic
valve, but lipid-lowering studies have had conflicting results. Methods We conducted a …

Known risk factors for coronary heart disease do not explain all of the clinical and
epidemiological features of the disease. To examine the role of chronic bacterial infections …

To investigate the regulation of serum levels of cholesterol precursor sterols and plant
sterols, these noncholesterol sterols, fatty acids, and various parame ters of cholesterol …

Objective: To determine the association between features of the insulin resistance syndrome
and Alzheimer's disease. Design: Cross sectional population based study. Subjects: 980 …

Objective—Genetic studies might provide new insights into the biological mechanisms
underlying lipid metabolism and risk of CAD. We therefore conducted a genome-wide …

The effects of alcohol intake on serum lipids and lipoproteins depend on the dose and mode
of alcohol intake, individual susceptibility, genetic variables, and dietary factors. Therefore …

Background and design The recent introduction of sensitive markers of myocardial injury is
likely to affect the epidemiology of coronary heart disease (CHD). The American Heart …

Background—Retrospective studies have suggested that patients with a low transvalvular
gradient in the presence of an aortic valve area< 1.0 cm2 and normal ejection fraction may …

Background LDL cholesterol has a causal role in the development of cardiovascular
disease. Improved understanding of the biological mechanisms that underlie the metabolism …