Signals from the TGF-βs are mediated by the TGF-β receptors and their substrates, the
Smad proteins. Inactivation of either of the two transmembrane serine/threonine kinases …

As interest has increased in the interaction between low-temperature plasmas and living
cells or organic materials, the role of modelling and simulation of atmospheric pressure …

Purpose The value of tumor-infiltrating lymphocytes (TILs) for prediction of pathologic
complete response (pCR) in breast cancer (BC) patients treated with neoadjuvant …

Background Patients who have residual invasive carcinoma after the receipt of neoadjuvant
chemotherapy for human epidermal growth factor receptor 2 (HER2)–negative breast cancer …

Background The poly (adenosine diphosphate–ribose) inhibitor talazoparib has shown
antitumor activity in patients with advanced breast cancer and germline mutations in BRCA1 …

Background CLEOPATRA was a phase 3 study comparing the efficacy and safety of
pertuzumab, trastuzumab, and docetaxel with placebo, trastuzumab, and docetaxel in …

Background The anti–human epidermal growth factor receptor 2 (HER2) humanized
monoclonal antibody trastuzumab improves the outcome in patients with HER2-positive …

Background Studies with pertuzumab, a novel anti-HER2 antibody, show improved efficacy
when combined with the established HER2-directed antibody trastuzumab in breast cancer …

Background In MONALEESA-2, ribociclib plus letrozole showed improved progression-free
survival compared with letrozole alone as first-line treatment for postmenopausal patients …

Background In the primary analysis of the NeoSphere trial, patients given neoadjuvant
pertuzumab, trastuzumab, and docetaxel showed a significantly improved pathological …