User profiles for "author:Yasuyuki Kihara"

Yasuyuki Kihara

Sanford Burnham Prebys Medical Discovery Institute
Verified email at sbpdiscovery.org
Cited by 4562

The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors

SPH Alexander, A Christopoulos… - British journal of …, 2019 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly …

Asian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea Symposium on Autoimmune Pancreatitis

M Otsuki, JB Chung, K Okazaki, MH Kim… - Journal of …, 2008 - Springer
Abstract In 2002, the Japan Pancreas Society (JPS) was the first in the world to propose
diagnostic criteria for autoimmune pancreatitis (AIP). Since the concept of AIP has changed …

Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy

A Groves, Y Kihara, J Chun - Journal of the neurological sciences, 2013 - Elsevier
Fingolimod is the first oral disease-modifying therapy approved for relapsing forms of
multiple sclerosis (MS). Following phosphorylation in vivo, the active agent, fingolimod …

The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors

SPH Alexander, A Christopoulos… - British journal of …, 2021 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the …

Lysophospholipid receptor nomenclature review: IUPHAR Review 8

Y Kihara, M Maceyka, S Spiegel… - British journal of …, 2014 - Wiley Online Library
Lysophospholipids encompass a diverse range of small, membrane‐derived phospholipids
that act as extracellular signals. The signalling properties are mediated by 7 …

Nonalcoholic fatty liver disease is a risk factor for type 2 diabetes in middle-aged Japanese men

M Shibata, Y Kihara, M Taguchi, M Tashiro… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—To determine the association between nonalcoholic fatty liver disease and the
risk for development of diabetes. RESEARCH DESIGN AND METHODS—We conducted an …

[HTML][HTML] Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6

K Yanagida, K Masago, H Nakanishi, Y Kihara… - Journal of Biological …, 2009 - ASBMB
p2y5 is an orphan G protein-coupled receptor that is closely related to the fourth
lysophosphatidic acid (LPA) receptor, LPA 4. Here we report that p2y5 is a novel LPA …

Lysophospholipid receptors in drug discovery

Y Kihara, H Mizuno, J Chun - Experimental cell research, 2015 - Elsevier
Lysophospholipids (LPs), including lysophosphatidic acid (LPA), sphingosine 1-phospate
(S1P), lysophosphatidylinositol (LPI), and lysophosphatidylserine (LysoPS), are bioactive …

[PDF][PDF] Crystal structure of antagonist bound human lysophosphatidic acid receptor 1

JE Chrencik, CB Roth, M Terakado, H Kurata, R Omi… - Cell, 2015 - cell.com
Lipid biology continues to emerge as an area of significant therapeutic interest, particularly
as the result of an enhanced understanding of the wealth of signaling molecules with …

[HTML][HTML] Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor

S Ishii, Y Kihara, T Shimizu - Journal of Biological Chemistry, 2005 - ASBMB
T cell death-associated gene 8 (TDAG8) is a G-protein-coupled receptor mainly expressed
in lymphoid organs and cancer tissues. TDAG8 shares high amino acid sequence …