[HTML][HTML] Signaling pathways and therapeutic interventions in gastric cancer

ZN Lei, QX Teng, Q Tian, W Chen, Y Xie… - Signal transduction and …, 2022 - nature.com
Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

[HTML][HTML] Targeting ferroptosis as a promising therapeutic strategy for ischemia-reperfusion injury

Y Pan, X Wang, X Liu, L Shen, Q Chen, Q Shu - Antioxidants, 2022 - mdpi.com
Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

[HTML][HTML] SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

J Luo, H Zou, Y Guo, T Tong, L Ye, C Zhu, L Deng… - Breast Cancer …, 2022 - Springer
Breast cancer (BC) has been ranked the most common malignant tumor throughout the
world and is also a leading cause of cancer-related deaths among women. SRC family …

[HTML][HTML] Structure analysis of the receptor binding of 2019-nCoV

Y Chen, Y Guo, Y Pan, ZJ Zhao - Biochemical and biophysical research …, 2020 - Elsevier
nCoV is a newly identified coronavirus with high similarity to SARS-CoV. We performed a
structural analysis of the receptor binding domain (RBD) of spike glycoprotein responsible …

An enzyme‐engineered nonporous copper (I) coordination polymer nanoplatform for cuproptosis‐based synergistic cancer therapy

Y Xu, SY Liu, L Zeng, H Ma, Y Zhang… - Advanced …, 2022 - Wiley Online Library
Cuproptosis, a newly identified form of regulated cell death that is copper‐dependent, offers
great opportunities for exploring the use of copper‐based nanomaterials inducing …

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

Y Huang, Z Xu, S Xiong, F Sun, G Qin, G Hu… - Nature …, 2018 - nature.com
Newborn microglia rapidly replenish the whole brain after selective elimination of most
microglia (> 99%) in adult mice. Previous studies reported that repopulated microglia were …

N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer

D Pflueger, DS Rickman, A Sboner, S Perner… - Neoplasia, 2009 - Elsevier
A step toward the molecular classification of prostate cancer was the discovery of recurrent
erythroblast transformation. specific rearrangements, most commonly fusing the androgen …

[HTML][HTML] Inhibition of Mcl-1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells

DA Luedtke, X Niu, Y Pan, J Zhao, S Liu… - Signal transduction and …, 2017 - nature.com
Acute myeloid leukemia (AML) is a serious disease. The 5-year survival rates remain
frustratingly low (65% for children and 26% for adults). Resistance to frontline chemotherapy …

[HTML][HTML] Associations of mental health and personal preventive measure compliance with exposure to COVID-19 information during work resumption following the …

Y Pan, M Xin, C Zhang, W Dong, Y Fang, W Wu… - Journal of medical …, 2020 - jmir.org
Background Risk and crisis communication plays an essential role in public health
emergency responses. The COVID-19 pandemic has triggered spontaneous and intensive …

[HTML][HTML] An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

N Li, R Babaei-Jadidi, F Lorenzi, B Spencer-Dene… - Oncogenesis, 2019 - nature.com
Colorectal cancer (CRC) patients develop recurrence after chemotherapy owing to the
survival of stem cell-like cells referred to as cancer stem-like cells (CSCs). The origin of …