[PDF][PDF] Immunology of COVID-19: current state of the science
Immunity, 2020•cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting
an unprecedented effort from the scientific community to understand the biological
underpinning of COVID19 pathophysiology. In this Review, we summarize the current state
of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection
and the immunological pathways that likely contribute to disease severity and death. We …
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting
an unprecedented effort from the scientific community to understand the biological
underpinning of COVID19 pathophysiology. In this Review, we summarize the current state
of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection
and the immunological pathways that likely contribute to disease severity and death. We …
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an unprecedented effort from the scientific community to understand the biological underpinning of COVID19 pathophysiology. In this Review, we summarize the current state of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection and the immunological pathways that likely contribute to disease severity and death. We also discuss the rationale and clinical outcome of current therapeutic strategies as well as prospective clinical trials to prevent or treat SARS-CoV-2 infection.
cell.com