User profiles for Stephen Safe

Stephen Safe

Professor of Toxicology, Texas A&M University
Verified email at cvm.tamu.edu
Cited by 94840

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β

…, JG Lemmen, BO Carlsson, JC Corton, SH Safe… - …, 1998 - academic.oup.com
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ,
which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation …

Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife.

…, RE Peterson, L Poellinger, S Safe… - Environmental …, 1998 - ehp.niehs.nih.gov
An expert meeting was organized by the World Health Organization (WHO) and held in
Stockholm on 15-18 June 1997. The objective of this meeting was to derive consensus toxic …

The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds

…, A Hanberg, L Haws, M Rose, S Safe… - Toxicological …, 2006 - academic.oup.com
In June 2005, a World Health Organization (WHO)-International Programme on Chemical
Safety expert meeting was held in Geneva during which the toxic equivalency factors (TEFs) …

Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment

SH Safe - Critical reviews in toxicology, 1994 - Taylor & Francis
Commercial polychlorinated biphenyls (PCBs) and environmental extracts contain complex
mixtures of congeners that can be unequivocally identified and quantitated. Some PCB …

Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations …

S Safe - Critical reviews in toxicology, 1990 - Taylor & Francis
Halogenated aromatic compounds, typified by the polychlorinated dibenzo-p-dioxins (PCDDs),
dibenzofurans (PCDFs), biphenyls (PCBs), and diphenylethers (PCDEs), are industrial …

Polychlorinated biphenyls (PCBs) and polybrominated biphenyls (PBBs): biochemistry, toxicology, and mechanism of action

S Safe, O Hutzinger - CRC Critical Reviews in Toxicology, 1984 - Taylor & Francis
Commercial polychlorinated biphenyl (PCB) and polybrominated biphenyl (PBB) are formulations
prepared by the chlorination and bromination, respectively, of biphenyl (Figure 1 The …

HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

…, G Johnson, J Frank, R Burghardt, S Kim, S Safe - Oncogene, 2013 - nature.com
HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb
Repressive Complex 2 (PRC2) and overexpression is correlated with poor survival for breast…

Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans

SH Safe - Annual review of pharmacology and toxicology, 1986 - annualreviews.org
Polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated di benzofurans (PCDFs)
are members of a chemical family (polyhalogenated aromatics) that also includes the …

High-resolution PCB analysis: synthesis and chromatographic properties of all 209 PCB congeners

…, M Romkes, SH Safe, LM Safe - … science & technology, 1984 - ACS Publications
High-Resolution PCB Analysis: Synthesis and Chromatographic Properties of All 209 PCB
Congeners Page 1 Environ. Sci. Technol. 1984, 18, 468-476 (34) Niki, H.; Maker, P. D.; Savage …

Sp transcription factor family and its role in cancer

S Safe, M Abdelrahim - European journal of cancer, 2005 - Elsevier
Specificity protein 1 (Sp1) and other Sp and Krüppel-like factor (KLF) proteins are members
of a family of transcription factors which bind GC/GT-rich promoter elements through three C …