BMJ gastroenterology COVID-19 collection

COVID-19 virus

This collection of articles highlights all research relating to the COVID-19 pandemic published by Gut, Frontline Gastroenterology and BMJ Open Gastroenterology. It will continue to grow as new articles are published.

In the current climate, it is vital that research into the disease is as accessible as possible for clinicians, healthcare workers and researchers across the globe. We hope that this collection of research into COVID-19 and gastroenterology will be a useful resource.

To explore more research, news, opinion pieces and resources published by The BMJ and all BMJ Journals, visit BMJ’s Coronavirus Hub. For the latest updates on research published by the journals and guidance from the British Society of Gastroenterology, be sure to follow @Gut_BMJ, @FrontGastro_BMJ , @BMJOpen_Gastro and @BritSocGastro on Twitter.

Jump to:
COVID-19 Clinical
COVID-19 Endoscopy
COVID-19 Basic Science
COVID-19 Epidemiology
COVID-19 GI Service
COVID-19 Hepatology

COVID-19 Clinical

Diarrhoea may be underestimated: a missing link in 2019 novel coronavirus
Gut, 26th February 2020, Letter

SARS-CoV-2 induced diarrhoea as onset symptom in patient with COVID-19
Gut, 5th February 2020, Letter

COVID-19 in gastroenterology: a clinical perspective
Gut, 20th March 2020, Letter

COVID-19 and the gastrointestinal tract: more than meets the eye
Gut, 9th April 2020, Commentary

Gastrointestinal Symptoms of 95 Cases with SARS-CoV-2 Infection
Gut, 2nd April 2020, Original Research

Faecal calprotectin indicates intestinal inflammation in COVID-19
Gut, 20th April 2020, Letter

COVID-19 and the gastrointestinal tract: emerging clinical data
Frontline Gastroenterology, 27th April 2020, Review

Severe liver failure during SARS-CoV-2 infection
Gut, 23rd April 2020, Letter

COVID-19 guidance in chronic diseases: a need to reach across the borders of the traditional medical specialities
Frontline Gastroenterology, 7th May 2020, Letter

GI symptoms as early signs of COVID-19 in hospitalised Italian patients
Gut, 14th May 2020, Letter

The price of being a doctor during the COVID-19 outbreak
Gut, 10th May 2020, Letter

Comparative study of the clinical characteristics and epidemiological trend of 244 COVID-19 infected children with or without GI symptoms
Gut, 19th May 2020, Letter

Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: a multicentre cohort study
Gut, 20th May 2020, Letter

Novelty in the gut: a systematic review and meta-analysis of the gastrointestinal manifestations of COVID-19
BMJ Open Gastroenterology, 25th May 2020, Gastrointestinal Infection

Prevalence, risk factors and clinical outcomes of COVID-19 in patients with a history of pancreatitis in Northern California
Gut, 3rd June 2020, Letter

Pneumatosis intestinalis in COVID-19
BMJ Open Gastroenterology, 9th June 2020, Case Report

Risk factors in patients with COVID-19 developing severe liver injury during hospitalisation
Gut, 22nd June 2020, Letter

GI symptoms and fever increase the risk of severe illness and death in patients with COVID-19
Gut, 30th June 2020, Letter

Reorganisation of faecal microbiota transplant services during the COVID-19 pandemic
Gut, 3rd July 2020, Guidelines

Alteration of taste or smell as a predictor of COVID-19
Gut, 3rd July 2020, Letter

COVID-19 and the gastrointestinal tract: recent data
Frontline Gastroenterology, 5th July 2020, Education

Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19
Gut, 20th July 2020, Original Research

Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching
Gut, 30th July 2020, Gastroduodenal

Gastrointestinal manifestations of COVID-19 in children: a systematic review and meta-analysis
Frontline Gastroenterology, 18th August 2020, Education

A nationwide cohort study with propensity score matching
Gut, 9th October 2020, Letter

Proton pump inhibitor or famotidine use and severe COVID-19 disease: a propensity score-matched territory-wide study
Gut, 4th December 2020, Letter

Proton pump inhibitors and the risk of severe COVID-19: a post-hoc analysis from the Korean nationwide cohort
Gut, 10th December 2020, Letter

Aerosol generation and droplet spread during nasogastric intubation in the COVID-19 era
Gut, 31st December 2020, Letter

Serotonin is elevated in COVID-19-associated diarrhoea
Gut, 5th January 2021, Letter

The value of anal swab RT-PCR for COVID-19 diagnosis in adult Indonesian patients
BMJ Open Gastroenterology, 19th May 2021, Infection

Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19
Gut, 2nd June 2021, Letter

Duality of the association between COVID-19 and acute pancreatitis
Gut, 3rd June 2021, Letter

Acute-on-chronic liver failure (ACLF) precipitated by severe alcoholic hepatitis: another collateral damage of the COVID-19 pandemic?
Gut, 17th June 2021, Letter

Identification of the source events for aerosol generation during oesophago-gastro-duodenoscopy
Gut, 29th June 2021, Original Research

Rapid resolution of COVID-19 after faecal microbiota transplantation
Gut, 6th July 2021, Letter

Comparison between non-pulmonary and pulmonary immune responses in a HIV decedent who succumbed to COVID-19
Gut, 10th August 2021, Letter

Diet quality and risk and severity of COVID-19: a prospective cohort study
Gut, 6th September 2021, COVID-19

Incidence of ‘new-onset’ constipation and associated factors during lockdown due to the COVID-19 pandemic
BMJ Open Gastroenterology, 16th September 2021, Motility

Proton-pump inhibitor use is not associated with severe COVID-19-related outcomes: a propensity score-weighted analysis of a national veteran cohort
Gut, 18th October 2021, Letter

Prevalence and outcomes of acute pancreatitis in COVID-19: a meta-analysis
Gut, 20th October 2021, Letter

SARS-CoV-2 infection is associated with an increased risk of idiopathic acute pancreatitis but not pancreatic exocrine insufficiency or diabetes: long-term results of the COVIDPAN study
Gut, 11th November 2021, Letter

Clinical characteristics, hospitalisation and mortality rates of COVID-19 among patients with coeliac disease in the USA: a multicentre network study
Gut, 11th November 2021, Letter


A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis
Gut, 3rd March 2020, Letter

An urgent need to institute COVID-19 testing in patients with IBD experiencing flares
Frontline Gastroenterology, 27th March 2020, Opinion

Covid-19 and immunomodulation in IBD
Gut, 17th April 2020, Recent advances in basic science

British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic
Gut, 17th April 2020, Guidelines

Covid-19 infection in Crohn’s disease under treatment with adalimumab
Gut, 20th April 2020, Letter

Outcomes of COVID-19 in 79 patients with IBD in Italy: an IG-IBD study
Gut, 30th April 2020, Original Research

Adaptations to the British Society of Gastroenterology guidelines on the management of acute severe UC in the context of the COVID-19 pandemic: a RAND appropriateness panel
Gut, 8th June 2020, Original Research

Organisational changes and challenges for inflammatory bowel disease services in the UK during the COVID-19 pandemic
Frontline Gastroenterology, 16th June 2020, Original Research

Infliximab for severe ulcerative colitis and subsequent SARS-CoV-2 pneumonia: a stone for two birds
Gut, 17th June 2020, Letter

Implications of recurrent SARS-CoV-2 outbreaks for IBD management
Frontline Gastroenterology, 24th June 2020, Review

Adaptations to the current ECCO/ESPGHAN guidelines on the management of paediatric acute severe colitis in the context of the COVID-19 pandemic: a RAND appropriateness panel
Gut, 1st September 2020, Original Article

COVID-19-related health anxieties and impact of specific interventions in patients with inflammatory bowel disease in the UK
Frontline Gastroenterology, 11th September 2020, Original Research

Effect of IBD medications on COVID-19 outcomes: results from an international registry
Gut, 20th October 2020, Original Research

Disease monitoring of biologic treatment in IBD: early impact and future implications of COVID-19 pandemic
Frontline Gastroenterology, 30th September 2020, Opinion

Life in lockdown: experiences of patients with IBD during COVID-19
BMJ Open Gastroenterology, 19th November 2020, IBD

COVID-19 and IBD drugs: should we change anything at the moment?
Gut, 19th November 2020, Commentary

Maintenance therapy with infliximab or vedolizumab in IBD is not associated with increased SARS-CoV-2 seroprevalence: UK experience in the 2020 pandemic
Gut, 12th February 2021, Letter

Depression, anxiety and stress among patients with inflammatory bowel disease during the COVID-19 pandemic: Australian national survey
BMJ Open Gastroenterology, 12th February 2021, IBD

COVID-19: impetus to the adoption of capsule endoscopy as a primary diagnostic tool?
Frontline Gastroenterology, 24th February 2021, Commentary

Association between 5-aminosalicylates in patients with IBD and risk of severe COVID-19: an artefactual result of research methodology?
Gut, 3rd March 2021, Letter

Risk factors for SARS-CoV-2 infection and course of COVID-19 disease in patients with IBD in the Veterans Affair Healthcare System
Gut, 22nd March 2021, Original Research

Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab
Gut, 7th April 2021, Original Research

Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD
Gut, 26th April 2021, Original Research

Point-of-care faecal calprotectin testing in patients with paediatric inflammatory bowel disease during the COVID-19 pandemic
BMJ Open Gastroenterology, 4th May 2021, IBD

Antibody response to SARS-CoV-2 among individuals with IBD diminishes over time: a serosurveillance cohort study
Gut, 2nd August 2021, Letter

Quality of life in patients with IBD during the COVID-19 pandemic in the Netherlands
BMJ Open Gastroenterology, 2nd July 2021, IBD

Impact of medical therapies for inflammatory bowel disease on the severity of COVID-19: a systematic review and meta-analysis
BMJ Open Gastroenterology, 1st November 2021, IBD

COVID-19 Endoscopy

Practice of Endoscopy during COVID-19 Pandemic: Position Statements of Asian Pacific Society of Digestive Endoscopy (APSDE-COVID Statements)
Gut, 2nd April 2020, Guidelines

The prevention of nosocomial SARS-CoV2 transmission in endoscopy: international recommendations and the need for a gold standard.
Gut, 2nd April 2020, Letter

Gastrointestinal endoscopy during COVID-19: when less is more
Frontline Gastroenterology, 15th April 2020, Commentary

Low risk of covid-19 transmission in GI endoscopy
Gut, 22nd April 2020, Endoscopy News

APSDE-COVID statements: recommendations should be modified according to the prevalence of COVID infection rates
Gut, 30th April 2020, Letter

Safely restarting GI endoscopy in the era of COVID-19
Gut, 5th June 2020, Leading Article

Impact of the COVID-19 outbreak on endoscopy training in a tertiary care centre in Germany
Frontline Gastroenterology, 10th June 2020, Education

COVID-19 and endoscopy training
Frontline Gastroenterology, 10th June 2020, Letter

Development and evaluation of a novel protective device for upper gastrointestinal endoscopy in the COVID-19 pandemic: the EBOX
Frontline Gastroenterology, 12th June 2020, Original Research

Data from a large Western centre exploring the impact of COVID-19 pandemic on endoscopy services and cancer diagnosis
Frontline Gastroenterology, 20th July 2020, Original Research

Protective enclosure for performing gastrointestinal endoscopy
Frontline Gastroenterology, 4th August 2020, Letter

Multicentre prospective study of COVID-19 transmission following outpatient GI endoscopy in the UK
Gut, 14th September 2020, Endoscopy News

Effects of SARS-CoV-2 emergency measures on high-risk lesions detection: a multicentre cross-sectional study
Gut, 28th September 2020, Endoscopy News

Clinical, financial and academic implications of COVID-19 on a tertiary care interventional endoscopy programme
Gut, 14th December 2020, Endoscopy News

Endoscopes used in positive and critically ill patients are SARS-CoV-2 negative at virological assessment
Gut, 6th January 2021, Endoscopy News

Adherence to recommendations for endoscopy practice during COVID-19 pandemic in Latin America: how are we doing it?
BMJ Open Gastroenterology, 12th January 2021, Endoscopy

Endoscopy training in the UK pre-COVID–19 environment: a multidisciplinary survey of endoscopy training and the experience of reciprocal feedback
Frontline Gastroenterology, 7th February 2021, Original Research

SARS-CoV-2 transmission via endoscopy in the COVID-19 era
Gut, 5th March 2021, Letter

COVID-19 transmission following outpatient endoscopy during pandemic acceleration phase involving SARS-CoV-2 VOC 202012/01 variant in UK
Gut, 24th March 2021, Endoscopy News

SARS-CoV-2 in endoscopy: a potential way of microorganisms’ air transmission
Gut, 5th May 2021, Letter

SARS-COV-2 in endoscopy: still a long way to go
Gut, 11th June 2021, Letter

Haemorrhagic ulcerative duodenitis in a patient with COVID-19 infection: clinical improvement following treatment with budesonide
BMJ Open Gastroenterology, 18th October 2021, Endoscopy

COVID-19 GI Service

Gastroenterology department operational reorganisation at the time of covid-19 outbreak: an Italian and Chinese experience
Gut, 16th April 2020, Leading Article

Gastrointestinal cancer pathways may breakdown due to COVID-19
Frontline Gastroenterology, 11th June 2020, Letter

Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: a National Endoscopy Database Analysis
Gut, 20th July 2020, Original Research

Clinical research during the COVID-19 pandemic: gastroenterology researchers’ perspective
Frontline Gastroenterology, 29th July 2020, Opinion

Recovery of endoscopy services in the era of COVID-19: recommendations from an international Delphi consensus
Gut, 14th August 2020, Guidelines

COVID-19 and its impact on endoscopy services: what is the threshold for missed malignant diagnosis?
Gut, 26th August 2020, Letter

Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study
Gut, 27th August 2020, Original Research

Triage guidance for upper gastrointestinal physiology investigations during restoration of services during the COVID-19 pandemic
Frontline Gastroenterology, 30th September 2020, Opinion

Exit strategies from the COVID-19 lockdown for children and young people receiving home parenteral nutrition (HPN): lessons from the BSPGHAN Intestinal Failure Working Group experience
Frontline Gastroenterology, 27th October 2020, Opinion

Mandatory preprocedure testing for SARS-CoV-2 for all-comers may not be required for resuming endoscopic services amidst the ongoing COVID-19 pandemic
Gut, 6th November 2020,  Letter

Impact of COVID-19 pandemic on key performance indicators in pancreatobiliary endoscopy: prioritise, minimise risk, keep scoping and training
Frontline Gastroenterology, 15th December 2020, Original Research

COVID-19 and endoscopic services: the impact of delays in therapeutic colonoscopies on patients
Gut, 4th February 2021, Letter

Gastroenterology 2021: from the heart of the COVID-19 pandemic
Frontline Gastroenterology, 5th February 2021, Opinion

COVID-19 Hepatology

Risk of severe illness from COVID-19 in patients with metabolic dysfunction-associated fatty liver disease and increased fibrosis
Gut, 15th May 2020, Letter

Prioritisation and the initiation of HCC surveillance in CHB patients: lessons to learn from the COVID-19 crisis
Gut, 25th May 2020, Leading Article

One world, one pandemic, many guidelines: management of liver diseases during COVID-19
Gut, 4th June, Leading Article

COVID-19 in an international European liver transplant recipient cohort
Gut, 22nd June 2020, Original Research

Liver injury is independently associated with adverse clinical outcomes in patients with COVID-19
Gut, 8th July 2020, Original Research

Comparison of mortality risk in patients with cirrhosis and COVID-19 compared with patients with cirrhosis alone and COVID-19 alone: multicentre matched cohort
Gut, 13th July 2020, Original Research

Involvement of liver in COVID-19: systematic review and meta-analysis
Gut, 15th July 2020, Letter

Liver stiffness by transient elastography accompanies illness severity in COVID-19
BMJ Open Gastroenterology, 13th July 2020, Hepatology

Modulating immunosuppression in liver transplant patients with COVID-19
Gut, 18th August 2020, Letter

COVID-19 in patients with cirrhosis: understanding adverse impact
Gut, 21st August 2020, Letter

Combination of CLIF-OF and CCI predicts survival in patients with cirrhosis and COVID-19
Gut, 7th October 2020, Letter

Severe alcohol-related liver disease admissions post-COVID-19 lockdown: canary in the coal mine?
Frontline Gastroenterology, 26th October 2020, Letter

Abnormal liver blood tests among hospitalised patients with SARS-CoV2 (COVID-19)
Frontline Gastroenterology, 2nd November 2020, Commentary

Liver dysfunction in COVID-19: a useful prognostic marker of severe disease?
Frontline Gastroenterology, 22nd December 2020, Original Research

Liver function test abnormalities at hospital admission are associated with severe course of SARS-CoV-2 infection: a prospective cohort study
Gut, 29th January 2021, Original Research

Liver injury, hypoalbuminaemia and severe SARS-CoV-2 infection
Gut, 2nd June 2021, Letter

Exercising in the COVID-19 era: implications in non-alcoholic fatty liver disease (NAFLD)
BMJ Open Gastroenterology, 24th June 2021, Communication

COVID-19 in liver transplant candidates: pretransplant and post-transplant outcomes – an ELITA/ELTR multicentre cohort study
Gut, 19th July 2021, Hepatology

Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned
BMJ Open Gastroenterology, 20th October 2021, Hepatology

Clinical outcomes in COVID-19 and cirrhosis: a systematic review and meta-analysis of observational studies
BMJ Open Gastroenterology, 21st October 2021, Hepatology