Top Cited Articles

We wanted to highlight our top cited research from the past 3 years to draw attention to the high quality, cutting edge research and reviews in the field of Gastroenterology and Hepatology. As a thank you to our authors and readers, we have made these articles free to access.

2018

Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study
Ka Shing Cheung, Esther W Chan, Angel Y. S. Wong, et al.
10.1136/gutjnl-2017-314605

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease
Floris Imhann, Arnau Vich Vila, Marc Jan Bonder, et al.
10.1136/gutjnl-2016-312135

European evidence-based guidelines on pancreatic cystic neoplasms
Marco Del Chiaro, Marc G. Besselink, Lianne Scholten on behalf of The European Study Group on Cystic Tumours of the Pancreas et al.
10.1136/gutjnl-2018-316027

Integrative analysis of exogenous, endogenous, tumour and immune factors for precision medicine
Shuji Ogino, Jonathan A. Nowak, Tsuyoshi Hamada, et al.
10.1136/gutjnl-2017-315537

Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study
Xiaozhou Fan, Alexander V. Alekseyenko, Jing Wu, et al.
10.1136/gutjnl-2016-312580

Bacterial and fungal infections in acute-on-chronic liver failure: prevalence, characteristics and impact on prognosis
Javier Fernandez, Juan Acevedo, Reiner Wiest, et al.
10.1136/gutjnl-2017-314240

Human gut microbiome: hopes, threats and promises
Patrice D. Cani
10.1136/gutjnl-2018-316723

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer
Thomas A. Mace, Reena Shakya, Jason R. Pitarresi, et al.
10.1136/gutjnl-2016-311585

Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome
Tao Zuo, Sunny H. Wong, Kelvin Lam, et al.
10.1136/gutjnl-2017-313952

The oral microbiota in colorectal cancer is distinctive and predictive
Burkhardt Flemer, Ryan D. Warren, Maurice P. Barrett, et al.
10.1136/gutjnl-2017-314814

2017

Global patterns and trends in colorectal cancer incidence and mortality
Melina Arnold, Monica S. Sierra, Mathieu Laversanne, et al.
10.1136/gutjnl-2015-310912

Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report
P Malfertheiner, F Megraud, C. A. O’Morain on behalf of the European Helicobacter and Microbiota Study Group and Consensus panel, et al.
10.1136/gutjnl-2016-312288

The safety of vedolizumab for ulcerative colitis and Crohn’s disease
Jean-Frederic Colombel, Bruce E. Sands, Paul Rutgeerts P, et al.
10.1136/gutjnl-2015-311079

European consensus conference on faecal microbiota transplantation in clinical practice
Giovanni Cammarota, Gianluca Ianiro, Herbert Tilg, et al.
10.1136/gutjnl-2016-313017

Fungal microbiota dysbiosis in IBD
Harry Sokol, Valentin Leducq, Hugues Aschard, et al.
10.1136/gutjnl-2015-310746

Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases
Leon A. Adams, Quentin M. Anstee, Herbert Tilg, et al.
10.1136/gutjnl-2017-313884

Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease
Yaron Rotman, Arun J. Sanyal
10.1136/gutjnl-2016-312431

Tumour-associated and non-tumour-associated microbiota in colorectal cancer
Burkhardt Flemer, Denise B. Lynch, Jillian M. R. Brown, et al.
10.1136/gutjnl-2015-309595

A microbial signature for Crohn’s disease
Victoria Pascal, Marta Pozuelo, Natalia Borruel, et al.
10.1136/gutjnl-2016-313235

Acute-on-chronic liver failure: an update
Ruben Hernaez, Elsa Sola, Richard Moreau, et al.
10.1136/gutjnl-2016-312670

2016

The gut microbiota and host health: a new clinical frontier
Julian R. Marchesi, David H. Adams, Francesca Fava, et al.
10.1136/gutjnl-2015-309990

Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
Maria Carlota Dao, Amandine Everard, Judith Aron-Wisnewsky, et al.
10.1136/gutjnl-2014-308778

Proton pump inhibitors affect the gut microbiome
Floris Imhann, Marc Jan Bonder, Arnau Vich Vila, et al.
10.1136/gutjnl-2015-310376

High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome
Francesca De Filippis, Nicoletta Pellegrini, Lucia Vannini, et al.
10.1136/gutjnl-2015-309957

Proton pump inhibitors alter the composition of the gut microbiota
Matthew A. Jackson, Julia K. Goodrich, Maria-Emanuela Maxan, et al.
10.1136/gutjnl-2015-310861

Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates
Doris Vandeputte, Gwen Falony, Sara Viera-Silva, et al.
10.1136/gutjnl-2015-309618

Proton pump inhibitor-responsive oesophageal eosinophilia: an entity challenging current diagnostic criteria for eosinophilic oesophagitis
Javier Molina-Infante, Albert J. Bredenoord, Edaire Cheng, et al.
10.1136/gutjnl-2015-310991

Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery
Thomas Reinert, Lone V. Schøler, Rune Thomsen, et al.
10.1136/gutjnl-2014-308859

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease
E Quevrain, M A. Maubert, C Michon, et al.
10.1136/gutjnl-2014-307649

Liver PPAR alpha is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
Alexandra Montagner, Arnaud Polizzi, Edwin Fouche, et al.
10.1136/gutjnl-2015-310798