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Sudden onset of multiple seborrhoeic keratoses in a patient with well-differentiated neuroendocrine tumours of the gut
  1. Veronika Schmidt1,2,
  2. Roland Blum3,
  3. Matthias Möhrenschlager4
  1. 1 Department of Research, Christine Kühne Center for Allergy Research and Education, Davos Wolfgang, Switzerland
  2. 2 Department of Dermatology, University Hospital Basel, Basel, Switzerland
  3. 3 Department of Dermatology, University Hospital Bern, Bern, Switzerland
  4. 4 Department of Dermatology, Hochgebirgsklinik Davos AG, Davos Wolfgang, Switzerland
  1. Correspondence to Dr Matthias Möhrenschlager, Department of Dermatology, Hochgebirgsklinik Davos AG, Davos-Wolfgang, Switzerland; matthias.moehrenschlager{at}hgk.ch

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Clinical presentation

A 63-year-old man presented with an increasing number of pruritic, light to dark brown papules affecting his scalp, forehead and trunk (figure 1). The skin lesions started growing approximately 2 years prior. Clinical diagnosis of seborrhoeic keratoses (SK) was confirmed by histopathological examination (figure 2). Work-up of new intermittent dragging pain localised on the lower right abdominal quadrant showed well-differentiated neuroendocrine tumours (G1; somatostatin receptor 2a (SSTR2A) positive) of the ileum and the appendix. The ileum tumour had a diameter of 16 mm, with muscularis propria infiltration, invasion of lymphatic as well as blood vessels, and …

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Footnotes

  • Correction notice This article has been corrected since it published Online First. The affiliation for Dr Blum has been updated.

  • Contributors VS and MM were involved in the initial drafting of the manuscript. RB revised the manuscript. The clinical picture was taken by MM and the microscopic pictures were taken by RB. All authors were involved in the final revision of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.