Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial

Masatoshi Kudo; Kazuomi Ueshima; Masafumi Ikeda; Takuji Torimura; Nobukazu Tanabe; Hiroshi Aikata; Namiki Izumi; Takahiro Yamasaki; Shunsuke Nojiri; Keisuke Hino; Hidetaka Tsumura; Teiji Kuzuya; Norio Isoda; Kohichiroh Yasui; Hajime Aino; Akio Ido; Naoto Kawabe; Kazuhiko Nakao; Yoshiyuki Wada; Osamu Yokosuka; Kenichi Yoshimura; Takuji Okusaka; Junji Furuse; Norihiro Kokudo; Kiwamu Okita; Philip James Johnson; Yasuaki Arai

doi:10.1136/gutjnl-2019-318934

Article info

PDF

XML

Hepatology

Original research

Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial

Authors

Masatoshi Kudo Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan PubMed articles Google scholar articles
Kazuomi Ueshima Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan PubMed articles Google scholar articles
Masafumi Ikeda Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan PubMed articles Google scholar articles
Takuji Torimura Department of Gastroenterology and Hepatology, Kurume University School of Medicine, Kurume, Japan PubMed articles Google scholar articles
Nobukazu Tanabe Department of Gastroenterology, National Hospital Organisation Sendai Medical Center, Sendai, Japan PubMed articles Google scholar articles
Hiroshi Aikata Department of Gastroenterology and Metabolism, Hiroshima University, Hiroshima, Japan PubMed articles Google scholar articles
Namiki Izumi Department of Gastroenterology, Musashino Red Cross Hospital, Tokyo, Japan PubMed articles Google scholar articles
Takahiro Yamasaki Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Ube-Yamaguchi, Japan PubMed articles Google scholar articles
Shunsuke Nojiri Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan PubMed articles Google scholar articles
Keisuke Hino Department of Hepatology and Pancreatology, Kawasaki Medical School, Kurashiki, Japan PubMed articles Google scholar articles
Hidetaka Tsumura Department of Gastroenterology and Hepatology, Hyogo Cancer Center, Akashi, Japan PubMed articles Google scholar articles
Teiji Kuzuya Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Norio Isoda Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan PubMed articles Google scholar articles
Kohichiroh Yasui Department of Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Hajime Aino Division of Gastroenterology, Department of Medicine, Social Insurance Tagawa Hospital, Tagawa, Japan PubMed articles Google scholar articles
Akio Ido Department of Gastroenterology and Hepatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan PubMed articles Google scholar articles
Naoto Kawabe Department of Liver, Biliary Tract and Pancreas Diseases, Fujita Health University School of Medicine, Aichi, Japan PubMed articles Google scholar articles
Kazuhiko Nakao Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan PubMed articles Google scholar articles
Yoshiyuki Wada Department of Hepato-Biliary-Pancreatic Surgery, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan PubMed articles Google scholar articles
Osamu Yokosuka Department of Gastroenterology, School of Medicine, Chiba University, Chiba, Japan PubMed articles Google scholar articles
Kenichi Yoshimura Center for Integrated Medical Research, Hiroshima University, Hiroshima, Japan PubMed articles Google scholar articles
Takuji Okusaka Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan PubMed articles Google scholar articles
Junji Furuse Department of Medical Oncology, Kyorin University Faculty of Medicine, Mitaka, Japan PubMed articles Google scholar articles
Norihiro Kokudo Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan PubMed articles Google scholar articles
Kiwamu Okita Deapartment of Medicine, Shunan Memorial Hospital, Kudamatsu, Yamaguchi, Japan PubMed articles Google scholar articles
Philip James Johnson Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK PubMed articles Google scholar articles
Yasuaki Arai Department of Diagnostic Radiology, National Cancer Center Hospital, Tokyo, Japan PubMed articles Google scholar articles
on behalf of the TACTICS study group
Google scholar articles

Correspondence to Dr Masatoshi Kudo, Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan; m-kudo{at}med.kindai.ac.jp

View Full Text

Citation

Kudo M, Ueshima K, Ikeda M on behalf of the TACTICS study group, et al

Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial

Gut 2020;69:1492-1501.

Publication history

Received May 1, 2019
Revised October 16, 2019
Accepted October 27, 2019
First published December 4, 2019.

Online issue publication

August 19, 2020

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

Log in using your username and password

Main menu

Log in using your username and password

You are here

Authors

Citation

Publication history

Request permissions

Copyright information

Read the full text or download the PDF:

Log in using your username and password